Thromboembolism remains a major concern associated with the use of BMHVs, and one of its leading causes could be cavitation, which has been reported to occur due to rapid closing of BMHV leaflets and consequent pressure drop. The aortic root geometry and the implantation rotation of BMHV significantly affect the leaflet kinematics and associated hemodynamics of BMHV and, consequently, may also initiate cavitation which has been investigated in this study. Two aortic roots, straight and bulged, were modelled, while three implantation rotation angles of BMHV were modelled, differing by 45°. ALE was employed as the FSI method, and blood was modelled as non-Newtonian. The results show that the closing velocity of one of the leaflets of a 0° rotated BMHV was 15% higher in bulged aorta as compared to straight aorta. The maximum closing velocity of fast closing leaflet was found to increase with the increasing implantation rotation of BMHV in bulged aorta, being, respectively, 8% and 19% higher for 45° and 90° rotated BMHV as compared to a 0° rotated BMHV. Consequently, it was observed that the pressure dropped below the vapour pressure for all the modelled implantation rotation angles of BMHV in bulged aorta near the leaflet tip. The maximum pressure drop across BMHV also increased with the increasing implantation rotation of BMHV in bulged aorta, being, respectively, 20% and 44% higher for 45° and 90° rotated BMHV as compared to a 0° rotated BMHV. The leaflet kinematics have been found liable to initiate cavitation.
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Zakaria MS et al (2017) Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting. Med Biol Eng Comput 55(9):1519–1548
De Tullio M, Pedrizzetti G, Verzicco R (2011) On the effect of aortic root geometry on the coronary entry-flow after a bileaflet mechanical heart valve implant: a numerical study. Acta Mech 216(1):147–163
Li C-P, Lu P-C (2012) Numerical comparison of the closing dynamics of a new trileaflet and a bileaflet mechanical aortic heart valve. J Artif Organs 15(4):364–374
Mirkhani N, Davoudi MR, Hanafizadeh P, Javidi D, Saffarian N (2016) On-X heart valve prosthesis: numerical simulation of hemodynamic performance in accelerating systole. Cardiovasc Eng Technol 7(3):223–237
Takiura K et al (2003) A new approach to detection of the cavitation on mechanical heart valves. ASAIO J 49(3):304–308
Graf T, Fischer H, Reul H, Rau G (1991) Cavitation potential of mechanical heart valve prostheses. Int J Artif Organs 14(3):169–174
Mohammadi H, Mequanint K (2011) Prosthetic aortic heart valves: modeling and design. Med Eng Phys 33(2):131–147
Chandran K, Lee C, Chen L (1994) Pressure field in the vicinity of mechanical valve occluders at the instant of valve closure: correlation with cavitation initiation. J Heart Valve Dis 3:S65–S75 (discussion S75-6)
Lai YG, Chandran KB, Lemmon J (2002) A numerical simulation of mechanical heart valve closure fluid dynamics. J Biomech 35(7):881–892
Lim W, Chew Y, Low H, Foo W (2003) Cavitation phenomena in mechanical heart valves: the role of squeeze flow velocity and contact area on cavitation initiation between two impinging rods. J Biomech 36(9):1269–1280
Chandran KB, Aluri S (1997) Mechanical valve closing dynamics: relationship between velocity of closing, pressure transients, and cavitation initiation. Ann Biomed Eng 25(6):926–938
Kini V, Bachmann C, Fontaine A, Deutsch S, Tarbell J (2000) Flow visualization in mechanical heart valves: occluder rebound and cavitation potential. Ann Biomed Eng 28(4):431–441
Johansen P (2004) Mechanical heart valve cavitation. Expert Rev Med Devices 1(1):95–104
Yoganathan AP, He Z, Casey Jones S (2004) Fluid mechanics of heart valves. Annu Rev Biomed Eng 6:331–362
Dexter EU et al (1998) In vivo demonstration of cavitation potential of a mechanical heart valve. Am Soc Artif Internal Organs 45(5):436–441
Lee H, Akagawa E, Tatsumi E, Taenaka Y (2008) Characteristics of cavitation intensity in a mechanical heart valve using a pulsatile device: synchronized analysis between visual images and pressure signals. J Artif Organs 11(2):60
Borazjani I, Ge L, Sotiropoulos F (2010) High-resolution fluid–structure interaction simulations of flow through a bi-leaflet mechanical heart valve in an anatomic aorta. Ann Biomed Eng 38(2):326–344
Annerel S et al (2012) A fast strong coupling algorithm for the partitioned fluid–structure interaction simulation of BMHVs. Comput Methods Biomech Biomed Eng 15(12):1281–1312
Hong T, Kim CN (2011) A numerical analysis of the blood flow around the bileaflet mechanical heart valves with different rotational implantation angles. J Hydrodyn 23(5):607–614
Haya L, Tavoularis S (2016) Effects of bileaflet mechanical heart valve orientation on fluid stresses and coronary flow. J Fluid Mech 806:129–164
Borazjani I, Sotiropoulos F (2010) The effect of implantation orientation of a bileaflet mechanical heart valve on kinematics and hemodynamics in an anatomic aorta. J Biomech Eng 132(11):111005
Grigioni M et al (2005) Three-dimensional numeric simulation of flow through an aortic bileaflet valve in a realistic model of aortic root. ASAIO J 51(3):176–183
Bang JS, Yoo SM, Kim CN (2006) Characteristics of pulsatile blood flow through the curved bileaflet mechanical heart valve installed in two different types of blood vessels: velocity and pressure of blood flow. ASAIO J 52(3):234–242
Khalili F, Gamage P, Mansy HA (2018) The influence of the aortic root geometry on flow characteristics of a bileaflet mechanical heart valve. arXiv preprint arXiv:1803.03362
Reul H, Vahlbruch A, Giersiepen M, Schmitz-Rode T, Hirtz V, Effert S (1990) The geometry of the aortic root in health, at valve disease and after valve replacement. J Biomech 23(2):181–191
Dumont K, Vierendeels J, Kaminsky R, Van Nooten G, Verdonck P, Bluestein D (2007) Comparison of the hemodynamic and thrombogenic performance of two bileaflet mechanical heart valves using a CFD/FSI model. J Biomech Eng 129(4):558–565
Hanafizadeh P, Mirkhani N, Davoudi MR, Masouminia M, Sadeghy K (2016) Non-Newtonian blood flow simulation of diastolic phase in bileaflet mechanical heart valve implanted in a realistic aortic root containing coronary arteries. Artif Organs 40(10):E179–E191
Weddell JC, Kwack J, Imoukhuede P, Masud A (2015) Hemodynamic analysis in an idealized artery tree: differences in wall shear stress between Newtonian and non-Newtonian blood models. PLoS ONE 10(4):e0124575
Gijsen F, Allanic E, Van de Vosse F, Janssen J (1999) The influence of the non-Newtonian properties of blood on the flow in large arteries: unsteady flow in a 90 curved tube. J Biomech 32(7):705–713
De Vita F, De Tullio M, Verzicco R (2016) Numerical simulation of the non-Newtonian blood flow through a mechanical aortic valve. Theor Comput Fluid Dyn 30(1–2):129–138
Caballero A, Laín S (2015) Numerical simulation of non-Newtonian blood flow dynamics in human thoracic aorta. Comput Methods Biomech Biomed Eng 18(11):1200–1216
Vlastos G, Lerche D, Koch B (1997) The superposition of steady on oscillatory shear and its effect on the viscoelasticity of human blood and a blood-like model fluid. Biorheology 34(1):19–36
Abbas SS, Nasif MS, Al-Waked R, Meor Said MA (2019) Numerical investigation on the effect of bileaflet mechanical heart valve’s implantation tilting angle and aortic root geometry on intermittent regurgitation and platelet activation. Artif Organs. https://doi.org/10.1111/aor.13536
Yin W, Gallocher S, Pinchuk L, Schoephoerster RT, Jesty J, Bluestein D (2005) Flow-induced platelet activation in a St. Jude mechanical heart valve, a trileaflet polymeric heart valve, and a St. Jude tissue valve. Artif Organs 29(10):826–831
Marom G (2015) Numerical methods for fluid–structure interaction models of aortic valves. Arch Comput Methods Eng 22(4):595–620
Yoganathan AP, Chandran K, Sotiropoulos F (2005) Flow in prosthetic heart valves: state-of-the-art and future directions. Ann Biomed Eng 33(12):1689–1694
Annerel S, Claessens T, Degroote J, Segers P, Vierendeels J (2014) Validation of a numerical FSI simulation of an aortic BMHV by in vitro PIV experiments. Med Eng Phys 36(8):1014–1023
Nobili M et al (2008) Numerical simulation of the dynamics of a bileaflet prosthetic heart valve using a fluid–structure interaction approach. J Biomech 41(11):2539–2550
Guivier-Curien C, Deplano V, Bertrand E (2009) Validation of a numerical 3-D fluid–structure interaction model for a prosthetic valve based on experimental PIV measurements. Med Eng Phys 31(8):986–993
Piatti F et al (2015) Hemodynamic and thrombogenic analysis of a trileaflet polymeric valve using a fluid–structure interaction approach. J Biomech 48(13):3641–3649
Gilmanov A, Stolarski H, Sotiropoulos F (2018) Flow–structure interaction simulations of the aortic heart valve at physiologic conditions: the Role of tissue constitutive model. J Biomech Eng 140(4):041003
Kadhim SK, Nasif MS, Al-Kayiem HH, Al-Waked R (2018) Computational fluid dynamics simulation of blood flow profile and shear stresses in bileaflet mechanical heart valve by using monolithic approach. Simulation 94(2):93–104
Dahl SK, Vierendeels J, Degroote J, Annerel S, Hellevik LR, Skallerud B (2012) FSI simulation of asymmetric mitral valve dynamics during diastolic filling. Comput Methods Biomech Biomed Eng 15(2):121–130
Dumont K, Stijnen J, Vierendeels J, Van De Vosse F, Verdonck P (2004) Validation of a fluid–structure interaction model of a heart valve using the dynamic mesh method in fluent. Comput Methods Biomech Biomed Eng 7(3):139–146
Vierendeels J, Dumont K, Verdonck P (2003) Stabilization of a fluid-structure coupling procedure for rigid body motion. In: 33rd AIAA fluid dynamics conference and exhibit, pp 23–26
Choi CR, Kim CN (2009) Numerical analysis on the hemodynamics and leaflet dynamics in a bileaflet mechanical heart valve using a fluid-structure interaction method. ASAIO J 55(5):428–437
Dasi L, Ge L, Simon H, Sotiropoulos F, Yoganathan A (2007) Vorticity dynamics of a bileaflet mechanical heart valve in an axisymmetric aorta. Phys Fluids 19(6):067105
Lee C, Chandran K, Chen L (1994) Cavitation dynamics of mechanical heart valve prostheses. Artif Organs 18(10):758–767
The authors are thankful to Universiti Teknologi PETRONAS for facilitating this research through its Graduate Assistantship (GA) scheme.
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Abbas, S.S., Nasif, M.S., Al-Waked, R. et al. Numerical investigation on the relationship of cavitation initiation in bileaflet mechanical heart valves (BMHVs) with the aortic root geometry and valve’s implantation rotation angle. J Braz. Soc. Mech. Sci. Eng. 42, 23 (2020) doi:10.1007/s40430-019-2108-x
- Fluid–structure interaction
- Closing dynamics of BMHVs