Neurobiology of Disordered Gambling
Gambling disorder affects 0.4 to 1.9 % of adults worldwide and is commonly associated with significant psychosocial dysfunction.
This article provides a concise primer on recent research examining the neurobiological underpinnings of gambling disorder.
Although impulsivity has been seen as one cognitive component underlying gambling disorder, compulsivity may be equally important to examine. Although causality remains elusive, structural and functional neuroimaging data suggest dysfunction in top-down executive control in gambling disorder. Recent twin research suggests that gambling disorder may have genetic links to both gambling and to obsessive-compulsive disorder.
Understanding the neurobiology of gambling disorder may lead to improved treatment approaches.
KeywordsGambling Cognition Neuroimaging Genetics
Compliance with Ethical Standards
Conflict of Interest
Dr. Jon Grant has received research grant support from NIDA, NCRG, Brainsway, TLC Foundation for Body Focused Repetitive Behaviors, the American Foundation for Suicide Prevention, Psyadon Pharmaceuticals, Forest Pharmaceuticals, Roche Pharmaceuticals, and Takeda Pharmaceuticals. He has also received royalties from American Psychiatric Publishing Inc., Oxford University Press, Norton, Johns Hopkins Press, and McGraw Hill Publishers.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
Papers of particular interest, published recently, have been highlighted as: • Of importance
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