European Archives of Paediatric Dentistry

, Volume 19, Issue 4, pp 205–220 | Cite as

Clinical and radiographic outcomes of laser pulpotomy in vital primary teeth: a systematic review and meta-analysis

  • H. Nematollahi
  • A. Sarraf Shirazi
  • M. Mehrabkhani
  • S. SabbaghEmail author
Systematic Review



This was to compare clinical and radiographic success rates of laser pulpotomy with those of other pulpotomy techniques in primary teeth.


PubMed, SCOPUS, EMBASE, Cochrane and ISI Web of Knowledge databases were searched electronically without time or language limitations. Clinical trials in which laser pulpotomy was compared with at least one other pulpotomy modality in primary teeth were selected. The bibliographic reference lists of eligible articles were also hand-searched. Odds ratios, risk differences and 95% confidence intervals were calculated with the aid of Comprehensive Meta-Analysis software (Version 2.2.050, Biostat, Englewood, NJ, USA). The methodological quality of articles included in the meta-analysis was determined using the Jadad scale.


Twelve pulpotomy studies were selected for systematic review and underwent data extraction. Of these studies, statistical analysis was conducted on 11. All clinical trials had low to moderate risks of methodological bias. The meta-analysis showed no significant differences in clinical and radiographic pulpotomy outcomes with laser compared with other techniques (p > 0.05). Likewise, no differences were found in the outcomes at 1, 3, 6, 9, 12 or ≥ 18 months (all p > 0.05).


For primary molar pulpotomy, the laser technique showed comparable clinical and radiographic results to other conventional pulpotomy medicaments, including formocresol and mineral trioxide aggregate.


Lasers Meta-analysis Pulpotomy Systematic review Primary teeth Treatment outcome 



No funding was received.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.


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Copyright information

© European Academy of Paediatric Dentistry 2018

Authors and Affiliations

  • H. Nematollahi
    • 1
    • 2
  • A. Sarraf Shirazi
    • 2
    • 3
  • M. Mehrabkhani
    • 1
    • 2
  • S. Sabbagh
    • 2
    • 4
    Email author
  1. 1.Dental Research CenterMashhad University of Medical SciencesMashhadIran
  2. 2.Department of Pediatric Dentistry, School of DentistryMashhad University of Medical SciencesMashhadIran
  3. 3.Dental Materials Research CenterMashhad University of Medical SciencesMashhadIran
  4. 4.Students Research CommitteeMashhad University of Medical SciencesMashhadIran

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