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European Archives of Paediatric Dentistry

, Volume 18, Issue 6, pp 419–422 | Cite as

Prevalence of oral lichen planus in Iranian children and adolescents: a 12-year retrospective study

  • S. Bakhtiari
  • J. B. Taheri
  • P. Toossi
  • S. AzimiEmail author
  • Sh. Kawosi Nezhad
Original Scientific Article
  • 122 Downloads

Abstract

Aim

To investigate the prevalence of oral lichen planus in patients younger than 18 years, referred to a dermatology centre in Iran during 2002–2014. Lichen planus is a chronic inflammatory, immune-mediated disease that could affect the oral mucosa and is a pre-cancerous condition. The disease usually develops in middle age with female predominance and is rare in children.

Methods

In this retrospective study, cases with definitive histopathologic diagnosis of lichen planus, over a 12-year period from 2002 to 2014 from a dermatologic hospital archive were evaluated. The prevalence of both cutaneous and oral lichen planus, the male:female ratio and site of involvement were calculated using SPSS version 21.

Results

Thirty-six of 564 patients younger than 18 years old diagnosed with lichen planus. Two females (0.4%) had oral lichen planus. One patient had erosive, and one had bullous, oral lichen planus.

Conclusion

Oral lichen planus had a very low frequency in Iranian population younger than 18 years old, identifying these patients is recommended for long-term follow-up.

Keywords

Oral Lichen planus Prevalence Children Adolescent 

Notes

Acknowledgements

The authors would like to thank Dr. Bakhshi from Shahid Beheshti University of Medical Science and Estie Kruger of the University of Western Australia for assistance and advice with this project.

Compliance with ethical standards

Funding

There is no source of funding for this study.

Conflict of interest

There is no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study was based on archives of the hospital. We confirm that patient information remained confidential and data were anonymised and non-identifiable prior to analysis.

References

  1. Alam F, Hamburger J. Oral mucosal lichen planus in children. Int J Paediatr Dent. 2001;11(3):209–14.CrossRefPubMedGoogle Scholar
  2. Balasubramaniam P, Ogboli M, Moss C. Lichen planus in children: review of 26 cases. Clin Exp Dermatol. 2008;33:457–9.CrossRefPubMedGoogle Scholar
  3. Chatterjee K, Bhattacharya S, Mukherjee C, Mazumdar A. A retrospective study of oral lichen planus in paediatric population. J Oral Maxillofac Pathol. 2012;16(3):363–7.CrossRefPubMedPubMedCentralGoogle Scholar
  4. Gorouhi F, Davari P, Fazel N. Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis. Sci World J 2014;2014:742826. doi: 10.1155/2014/742826.
  5. Gunashekhar M, Sudhakar R, Shahul M, et al. Oral lichen planus in childhood: a rare case report. Dermatol Online J. 2012;16(8):9.Google Scholar
  6. Gupta S, Chaudhari ND, Gupta A, Talanikar HV. Lichen planus-An update. Int J Pharm Biomed Sci. 2013;4(2):59–65.Google Scholar
  7. Handa S, Sahoo B. Childhood lichen planus: a study of 87 cases. Int J Dermatol. 2002;41(7):423–7.CrossRefPubMedGoogle Scholar
  8. Kanwar AJ, De D. Lichen planus in childhood: report of 100 cases. Clin Exp Dermatol. 2009;35(3):257–62.CrossRefPubMedGoogle Scholar
  9. Kumar V, Garg BR, Baruah MC, Vasireddi SS. Childhood lichen planus (LP). J Dermatol. 1993;20:175–7.CrossRefPubMedGoogle Scholar
  10. Laeijendecker R, Van Joost T, Tank B, Oranje A, Neumann M. Oral lichen planus in childhood. Pediatr Dermatol. 2005;22(4):299–304.CrossRefPubMedGoogle Scholar
  11. Luis-Montoya P, Domínguez-Soto L, Vega-Memije E. Lichen planus in 24 children with review of the literature. Pediatr Dermatol. 2005;22(4):295–8.CrossRefPubMedGoogle Scholar
  12. Nanda A, Al-Ajami HS, Al-Sabah H, Al-Hasawi F, Alsaleh QA. Childhood lichen planus: a report of 23 cases. Pediatr Dermatol. 2001;18(1):1–4.CrossRefPubMedGoogle Scholar
  13. Nevil BW, Damm DD, Allen CM, Chi AC. Oral and maxillofacial pathology. 4th ed. Saunders, St. Louis, MO: Elsevier; 2016.Google Scholar
  14. Nnoruka EN. Lichen planus in African children: a study of 13 patients. Pediatr Dermatol. 2007;24(5):495–8.CrossRefPubMedGoogle Scholar
  15. Parashar P. Oral lichen planus. Otolaryngol Clin N Am. 2011;44(1):89–107.CrossRefGoogle Scholar
  16. Patel S, Yeoman CM, Murphy R. Oral lichen planus in childhood: a report of three cases. Int J Paediatr Dent. 2005;15(2):118–22.CrossRefPubMedGoogle Scholar
  17. Puri N, Puri A. A study on lichen planus in children. Our Dermatol Online. 2013;4(3):303–5.CrossRefGoogle Scholar
  18. Schlosser BJ. Lichen planus and lichenoid reaction of the oral mucosa. Dermatol Ther. 2010;23(3):251–67.CrossRefPubMedGoogle Scholar
  19. Sharma R, Maheshwari V. Childhood lichen planus: a report of fifty cases. Pediatr Dermatol. 1999;16(5):345–8.CrossRefPubMedGoogle Scholar
  20. Shen ZY, Liu W, Zhu LK, et al. A retrospective clinicopathological study on oral lichen planus and malignant transformation: analysis of 518 cases. Med Oral Patol Oral Cir Bucal. 2012;17(6):e943–7.CrossRefPubMedPubMedCentralGoogle Scholar
  21. Walton KE, Bowers EV, Drolet BA, Holland KE. Childhood lichen planus: demographics of a U.S. population. Pediatr Dermatol. 2010;27(1):34–8.CrossRefPubMedGoogle Scholar
  22. Yardimci G, Kutlubay Z, Engin B, Tuzun Y. Precancerous lesions of oral mucosa. World J Clin Cases. 2014;2(12):866–72.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© European Academy of Paediatric Dentistry 2017

Authors and Affiliations

  • S. Bakhtiari
    • 1
  • J. B. Taheri
    • 1
  • P. Toossi
    • 2
  • S. Azimi
    • 3
    • 5
    Email author
  • Sh. Kawosi Nezhad
    • 4
  1. 1.Department of Oral Medicine, Dental SchoolShahid Beheshti University of Medical SciencesTehranIran
  2. 2.Department of Dermatology, Skin Research CenterShahid Beheshti University of Medical SciencesTehranIran
  3. 3.International Research Collaborative, Oral Health and Equity, School of Human SciencesThe University of Western AustraliaPerthAustralia
  4. 4.Dental SchoolShahid Beheshti University of Medical SciencesTehranIran
  5. 5.School of Human ScienceThe University of Western AustraliaCrawleyAustralia

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