European Archives of Paediatric Dentistry

, Volume 18, Issue 1, pp 59–63 | Cite as

Regional early development and eruption of permanent teeth: case report

  • A. M. Al MullahiEmail author
  • A. Bakathir
  • S. Al Jahdhami
Case Report



Early development and eruption of permanent teeth are rarely reported in scientific literature. Early eruption of permanent teeth has been reported to occur due to local factors such as trauma or dental abscesses in primary teeth, and in systemic conditions. Congenital diffuse infiltrating facial lipomatosis (CDIFL) is a rare condition that belongs to a group of lipomatosis tumours. In this disorder, the mature adipocytes invade adjacent soft and hard tissues in the facial region. Accelerated tooth eruption is one of the dental anomalies associated with CDIFL.

Case report

A 3-year-old boy presented with a swelling of the lower lip localised early development and eruption of permanent teeth and dental caries involving many primary teeth.


The planned treatment included biopsy of the swollen lower lip to confirm the diagnosis, surgical reduction and reconstruction of lip aesthetics. The management of the carious primary teeth included preventative and comprehensive dental care and extractions. These procedures were completed under general anaesthesia due to the child’s young age and poor cooperation. The lip biopsy showed features of CDIFL such as the presence of infiltrating adipose tissue, prominent number of nerve bundles and thickened vessels.


The high recurrence rate of CDIFL mandates long-term monitoring during the facial growth period of the child. Follow-up care by the paediatric dentist and maxillofacial surgeon has been required to manage all aspects of this congenital malformation.


This rare disorder has many implications affecting child’s facial aesthetics, psychological well being, developing occlusion and risk of dental caries. A multi-disciplinary approach is needed for management of this condition.


Congenital Lipomatosis Lower lip Tooth eruption 


Compliance with ethical standard

This article does not contain any studies with human participants or animals performed by any of the authors. There was no funding for this case report.

Conflict of interest

The authors declare that they have no conflict of interest.


  1. Almonaitiene R, Balciuniene I, Tutkuviene J. Factors influencing permanent teeth eruption: part one-general factors. Stomatologija. 2010;12:67–72.PubMedGoogle Scholar
  2. Chandna S, Bathla M. Oral manifestations of thyroid disorders and its management. Indian J Endocrinol Metab. 2011;15(2):S113–6.CrossRefPubMedPubMedCentralGoogle Scholar
  3. De Rosa G, Cozzolino A, Guarino M, Giardino C. Congenital infiltrating lipomatosis of the face: report of cases and review of the literature. J Oral Maxillofac Surg. 1987;45(10):879–83.CrossRefPubMedGoogle Scholar
  4. Dionne GP, Seemayer TA. Infiltrating lipomas and angiolipomas revisited. Cancer. 1974;33(3):732–8.CrossRefPubMedGoogle Scholar
  5. Kamal D, Breton P, Bouletreau P. Congenital infiltrating lipomatosis of the face: report of three cases and review of the literature. J Craniomaxillofac Surg. 2010;38(8):610–4.CrossRefPubMedGoogle Scholar
  6. Kang N, Ross D, Harrison D. Unilateral hypertrophy of the face associated with infiltrating lipomatosis. J Oral Maxillofac Surg. 1998;56(7):885–7.CrossRefPubMedGoogle Scholar
  7. Kjær I. Mechanism of human tooth eruption: review article including a new theory for future studies on the eruption process. Scientifica. 2014;2014:341905.CrossRefPubMedPubMedCentralGoogle Scholar
  8. Koch G, Poulsen S. Pediatric dentistry: a clinical approach, 2nd ed. Hoboken:Wiley-Blackwell; 2009.Google Scholar
  9. Lal S, Cheng B, Kaplan S, et al. Accelerated tooth eruption in children with diabetes mellitus. Pediatrics. 2008;121:1139–43.CrossRefGoogle Scholar
  10. Macmillan AR, Oliver AJ, Reade PC. Regional Macrodontia and regional bony enlargement associated with congenital infiltrating lipomatosis of the face presenting as unilateral facial hyperplasic brief review and case report. Int J Oral Maxillofac Surg. 1990;19(5):283–6.CrossRefPubMedGoogle Scholar
  11. Mahadevappa A, Raghavan VH, Ravishankar S, Manjunath GV. Congenital infiltrating lipomatosis of the face: a case report. Case Rep Pediatr. 2012;2012:134646.PubMedPubMedCentralGoogle Scholar
  12. Padwa BL, Mulliken JB. Facial infiltrating lipomatosis. Plast Reconstr Surg. 2001;108(6):1544–54.CrossRefPubMedGoogle Scholar
  13. Proffit WR, Frazier-Bowers SA. Mechanism and control of tooth eruption: overview and clinical implications. Orthod Craniofac Res. 2009;12:59–66.CrossRefPubMedGoogle Scholar
  14. Singer S, Pinhas-Hamiel O, Botzer E. Accelerated dental development as a presenting symptom of 21-hydroxylase deficient non-classic congenital adrenal hyperplasia. Clin Pediatr. 2001;40:621–3.CrossRefGoogle Scholar
  15. Singh K, Sen P, Musgrove BT, Thakker N. Facial infiltrating lipomatosis: a case report and review of literature. Int J Surg Case Rep. 2011;2(7):201–5.CrossRefPubMedPubMedCentralGoogle Scholar
  16. Slavin SA, Baker DC, McCarthy JG, Mufarrij A. Congenital infiltrating lipomatosis of the face: clinicopathologic evaluation and treatment. Plast Reconstr Surg. 1983;72(2):158–64.CrossRefPubMedGoogle Scholar
  17. Van Wingerden JJ, Erlank JD, Becker JH. Liposuction for congenital infiltrating lipomatosis of the face. Plast Reconstr Surg. 1988;81(6):989.CrossRefPubMedGoogle Scholar

Copyright information

© European Academy of Paediatric Dentistry 2016

Authors and Affiliations

  • A. M. Al Mullahi
    • 1
    Email author
  • A. Bakathir
    • 1
  • S. Al Jahdhami
    • 2
  1. 1.Oral Health DepartmentSultan Qaboos University HospitalMuscatSultanate of Oman
  2. 2.Pathology DepartmentSultan Qaboos University HospitalMuscatSultanate of Oman

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