European Archives of Paediatric Dentistry

, Volume 17, Issue 3, pp 195–203 | Cite as

Dental treatment for people with cystic fibrosis

  • N. HarringtonEmail author
  • P. J. Barry
  • S. M. Barry
Original Scientific Article



To describe the nature and consequences of the multi-system genetic condition cystic fibrosis with a view to ensuring optimal dental treatment planning for these patients.


A literature search was conducted to identify the key medical and dental manifestations of cystic fibrosis. These findings are discussed and utilised to create recommendations for treatment planning in patients with cystic fibrosis for the practising dental practitioner.


Cystic fibrosis is a complex, lethal, multisystem autosomal recessive disorder resulting from mutations on chromosome 7 which result in dysfunction of an ion channel that sits on epithelial surfaces. Respiratory disease remains the leading cause of mortality. Survival has greatly increased in recent decades secondary to improved treatment and specialist care. Specific dental manifestations of the disease may result from the condition itself or complications of treatment. Modification of patient management may be necessary to provide optimum patient care.


The pathophysiology and clinical manifestations are relevant to practicing dental practitioners and inform recommendations to be utilised to ensure optimal treatment planning for these patients.


Cystic fibrosis Caries Respiratory Dental 



The authors would like to acknowledge the kind contribution of the clinical image by Dr. Rowland Bright-Thomas, Manchester Adult CF Centre.

Compliance with Ethical Standards

Conflict of interest

PB has received honoraria and financial support for educational activities from Vertex pharmaceuticals Ltd.

This article does not contain any studies with human participants or animals performed by any of the authors.


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Copyright information

© European Academy of Paediatric Dentistry 2016

Authors and Affiliations

  1. 1.Department of Paediatric DentistryUniversity Dental Hospital ManchesterManchesterUK
  2. 2.University of ManchesterManchesterUK
  3. 3.Manchester Adult Cystic Fibrosis, University Hospital of South ManchesterManchesterUK
  4. 4.Institute of Inflammation and Repair, University of ManchesterManchesterUK

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