Biodentine™ material characteristics and clinical applications: a review of the literature
- 2.1k Downloads
Biodentine™ is a new version of calcium silicate-based inorganic cement.
The aim of this review is to provide a detailed analysis of the physical and biological properties of Biodentine™ and to compare these properties with those of other tricalcium silicate cements viz. mineral trioxide aggregate (MTA) and Bioaggregate™ (Bioaggregate).
A comprehensive systematic literature search for all publications to date was performed on 20th November 2013 by two independent reviewers in Medline (PubMed), Embase, Web of Science, CENTRAL (Cochrane), SIGLE, SciELO, Scopus, Lilacs and clinicaltrials.gov using the search terms Biodentine, “tricalcium silicate”, Ca3SiO5, “dentine substitute”, “dentin substitute” and RD 94. In addition to the electronic search, hand searches and reference searches were performed to include articles published in journals that were not indexed in Medline. Randomised control trials (RCT), case control studies, case series, case reports, in vitro studies, animal studies and short communications in English language were considered for this review.
Considering the superior physical and biologic properties, Biodentine™ could be an efficient alternative to MTA to be used in a variety of clinical applications. There appears to be a wide range of clinical applications where Biodentine™ could be used in the field of endodontics, dental traumatology, restorative dentistry and pediatric dentistry. Although it seems to be good clinical practice, currently there is little clinical evidence to support all potential indications.
Conflict of interest
The authors did not receive any funding and report no conflict of interest.
- Camilleri J, Grech L, Galea K, et al. Porosity and root dentine to material interface assessment of calcium silicate-based root-end filling materials. Clin Oral Investig 2013a [Epub ahead of print].Google Scholar
- Camilleri J, Sorrentino F, Damidot D. Investigation of the hydration and bioactivity of radiopacified tricalcium silicate cement, Biodentine and MTA Angelus. Dent Mater 2013b;29:580–593.Google Scholar
- Dammaschke T. A new bioactive cement for direct pulp capping International Dentistry—Australasian edition. 2012;7:52–8.Google Scholar
- De Souza ET, Nunes Tameirao MD, Roter JM, et al. Tridimensional quantitative porosity characterization of three set calcium silicate-based repair cements for endodontic use. Microsc Res Tech 2013;76:1093–8.Google Scholar
- Goldberg M, Pradelle-Plasse N, Tran XV, Colon P. Emerging trends in Biomaterials; VI-2-1 physico-chemical properties. Oxfordshire: Coxmoor Publishing Company; 2009.Google Scholar
- Khan SIR, Ramachandran A, Deepalakshmi M, Kumar KS. Evaluation of pH and calcium ion release of mineral trioxide aggregate and a new root-end filling material. E J Dentistry. 2012;2:166–9.Google Scholar
- Kokate SR, Pawar AM. An in vitro comparative stereomicroscopic evaluation of marginal seal between MTA, glass inomer cement and biodentine as root end filling materials using 1 % methylene blue as tracer. Endodontology. 2012;24:36–42.Google Scholar
- Meschack RA, Velkrishna K, Chakravarthy P, Nerali J. Overview of root end filling materials. Int J Clin Dental Sci. 2012;3:63–9.Google Scholar
- Nikhil V, Arora V, Jha P, Verma M. Non surgical management of trauma induced external root resorption at two different sites in a single tooth with Biodentine: a case report. Endodontology. 2012;24:150–5.Google Scholar
- Rada RE. New options for restoring a deep carious lesion. Dent Today. 2013;32(102):104–5.Google Scholar