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Sports Medicine

, Volume 49, Issue 1, pp 9–15 | Cite as

Fat-Free Adipose Tissue Mass: Impact on Peak Oxygen Uptake (VO2peak) in Adolescents with and without Obesity

  • Takashi AbeEmail author
  • Jeremy P. Loenneke
  • Robert S. Thiebaud
Review Article

Abstract

Fat-free body mass (FFM) is a surrogate for skeletal muscle mass and is often used for the normalization of several physiological variables (e.g., oxygen uptake). However, FFM includes non-skeletal muscle components such as the fat-free component of adipose tissue fat cells. As the amount of adipose tissue mass increases, the FFM will also increase and be included in the measurement of FFM. Therefore, FFM may not be an appropriate indicator of muscle mass when targeting individuals with a large amount of body fat. This review aimed (1) to examine the fat-free adipose tissue (FFAT) in adolescents with and without obesity and (2) to investigate the impact of FFAT on peak oxygen uptake (VO2peak) by comparing VO2peak expressed relative to FFM and FFM minus FFAT between adolescents with and without obesity. Calculated FFAT was threefold higher in adolescents with obesity compared to those without obesity (mean ± SD; 6.94 ± 1.40 vs. 2.22 ± 0.58 kg). The VO2peak expressed relative to FFM-FFAT was similar between the two groups (56.5 ± 6.7 vs. 57.4 ± 8.9 ml min−1 kg−1 FFM-FFAT, respectively). On the other hand, VO2peak expressed relative to FFM was approximately 8% different between groups. When normalizing VO2peak by FFM, eliminating the FFAT component from FFM may be needed, especially when comparing groups with different body fat mass.

Notes

Acknowledgements

We would like to thank Scott J. Dankel for his analytical contribution to our manuscript.

Compliance with Ethical Standards

Funding

No sources of funding were used to assist in the preparation of this article.

Conflict of interest

Takashi Abe, Jeremy Loenneke, and Robert Thiebaud declare that they have no conflicts of interest relevant to the content of this review.

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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.Department of Health, Exercise Science, and Recreation Management, Kevser Ermin Applied Physiology LaboratoryThe University of MississippiUniversityUSA
  2. 2.Department of KinesiologyTexas Wesleyan UniversityFort WorthUSA

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