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Sports Medicine

, Volume 48, Issue 11, pp 2463–2477 | Cite as

Athlete’s Heart: Diagnostic Challenges and Future Perspectives

  • Carlo De Innocentiis
  • Fabrizio Ricci
  • Mohammed Y. Khanji
  • Nay Aung
  • Claudio Tana
  • Elvira Verrengia
  • Steffen E. Petersen
  • Sabina Gallina
Review Article

Abstract

Distinguishing between adaptive and maladaptive cardiovascular response to exercise is crucial to prevent the unnecessary termination of an athlete’s career and to minimize the risk of sudden death. This is a challenging task essentially due to the substantial phenotypic overlap between electrical and structural changes seen in the physiological athletic heart remodeling and pathological changes seen in inherited or acquired cardiomyopathies. Stress testing is an ideal tool to discriminate normal from abnormal cardiovascular response by unmasking subtle pathologic responses otherwise undetectable at rest. Treadmill or bicycle electrocardiography, transthoracic echocardiography, and cardiopulmonary exercise testing are common clinical investigations used in sports cardiology, specifically among participants presenting with resting electrocardiographic abnormalities, frequent premature ventricular beats, or non-sustained ventricular arrhythmias. In this setting, as well as in cases of left ventricular hypertrophy or asymptomatic left ventricular dysfunction, stress imaging and myocardial tissue characterization by cardiovascular magnetic resonance show promise. In this review, we aimed to reappraise current diagnostic schemes, screening strategies and novel approaches that may be used to distinguish adaptive remodeling patterns to physical exercise from early phenotypes of inherited or acquired pathological conditions commanding prompt intervention.

Notes

Compliance with Ethical Standards

Conflict of interest

Carlo De Innocentiis, Fabrizio Ricci, Mohammed Y Khanji, Nay Aung, Claudio Tana, Elvira Verrengia, Steffen E Petersen, and Sabina Gallina declare that they have no conflicts of interest.

Funding

No financial support was received for the conduct of this study or preparation of this manuscript.

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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.Department of Neuroscience, Imaging and Clinical Sciences, Institute of Cardiology“G. d’Annunzio” UniversityChietiItaly
  2. 2.Department of Neuroscience, Imaging and Clinical Sciences, Institute for Advanced Biomedical Technologies“G. d’Annunzio” University of Chieti-PescaraChietiItaly
  3. 3.Department of Clinical Sciences, Malmö, Faculty of Medicine, Clinical Research CenterLund UniversityMalmöSweden
  4. 4.William Harvey Research Institute, NIHR Barts Biomedical Research CentreQueen Mary University of LondonLondonUK
  5. 5.Barts Heart CentreSt Bartholomew’s Hospital, Barts Health NHS TrustLondonUK
  6. 6.Internal Medicine and Critical Subacute Care Unit, Medicine and Geriatrics Rehabilitation DepartmentUniversity-Hospital of ParmaParmaItaly

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