Author’s Reply to Kitic: Comment on: “Association Between Exercise-Induced Hyperthermia and Intestinal Permeability: A Systematic Review”
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We appreciate the interest in our recent systematic review  and welcome the opportunity to reply to Dr. Cecilia Kitic , who argued that the strength of the association between exercise hyperthermia and intestinal permeability was artificially increased by the incorrect exclusion of an eligible study  and the inclusion of resting measures of core body temperature (TCORE) and the lactulose-to-rhamnose ratio. We disagree with the comments made by Dr. Kitic , and our reply to them is based on five lines of reasoning.
Firstly, we are sorry for the mistake regarding the method used by Shing et al.  to measure intestinal permeability. We also failed to correctly explain the reason for excluding this study from the correlation analysis. The study was excluded because the absolute values of the lactulose-to-rhamnose ratio were not reported at all in the manuscript. The only numerical statement regarding the ratio was given on page 99: “The ratio of...
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No sources of funding were used to assist in the preparation of this letter.
Conflicts of interest
Washington Pires, Samuel Wanner, Danusa Soares, and Cândido Coimbra have no conflicts of interest relevant to the content of this letter.