Sports Medicine

, Volume 46, Issue 11, pp 1689–1697 | Cite as

Effects of Resistance Training Frequency on Measures of Muscle Hypertrophy: A Systematic Review and Meta-Analysis

  • Brad J. Schoenfeld
  • Dan Ogborn
  • James W. Krieger
Systematic Review

Abstract

Background

A number of resistance training (RT) program variables can be manipulated to maximize muscular hypertrophy. One variable of primary interest in this regard is RT frequency. Frequency can refer to the number of resistance training sessions performed in a given period of time, as well as to the number of times a specific muscle group is trained over a given period of time.

Objective

We conducted a systematic review and meta-analysis to determine the effects of resistance training frequency on hypertrophic outcomes.

Methods

Studies were deemed eligible for inclusion if they met the following criteria: (1) were an experimental trial published in an English-language refereed journal; (2) directly compared different weekly resistance training frequencies in traditional dynamic exercise using coupled concentric and eccentric actions; (3) measured morphologic changes via biopsy, imaging, circumference, and/or densitometry; (4) had a minimum duration of 4 weeks; and (5) used human participants without chronic disease or injury. A total of ten studies were identified that investigated RT frequency in accordance with the criteria outlined.

Results

Analysis using binary frequency as a predictor variable revealed a significant impact of training frequency on hypertrophy effect size (P = 0.002), with higher frequency being associated with a greater effect size than lower frequency (0.49 ± 0.08 vs. 0.30 ± 0.07, respectively). Statistical analyses of studies investigating training session frequency when groups are matched for frequency of training per muscle group could not be carried out and reliable estimates could not be generated due to inadequate sample size.

Conclusions

When comparing studies that investigated training muscle groups between 1 to 3 days per week on a volume-equated basis, the current body of evidence indicates that frequencies of training twice a week promote superior hypertrophic outcomes to once a week. It can therefore be inferred that the major muscle groups should be trained at least twice a week to maximize muscle growth; whether training a muscle group three times per week is superior to a twice-per-week protocol remains to be determined.

References

  1. 1.
    Schoenfeld BJ. The mechanisms of muscle hypertrophy and their application to resistance training. J Strength Cond Res. 2010;24(10):2857–72.CrossRefPubMedGoogle Scholar
  2. 2.
    Hubal MJ, Gordish-Dressman H, Thompson PD, et al. Variability in muscle size and strength gain after unilateral resistance training. Med Sci Sports Exerc. 2005;37(6):964–72.PubMedGoogle Scholar
  3. 3.
    Bamman MM, Petrella JK, Kim JS, et al. Cluster analysis tests the importance of myogenic gene expression during myofiber hypertrophy in humans. J Appl Physiol. 2007;102(6):2232–9.CrossRefPubMedGoogle Scholar
  4. 4.
    Schoenfeld BJ, Ratamess NA, Peterson MD, et al. Effects of different volume-equated resistance training loading strategies on muscular adaptations in well-trained men. J Strength Cond Res. 2014;28(10):2909–18.CrossRefPubMedGoogle Scholar
  5. 5.
    Schoenfeld BJ, Peterson MD, Ogborn D, et al. Effects of low- versus high-load resistance training on muscle strength and hypertrophy in well-trained men. J Strength Cond Res. 2015;29(10):2954–63.CrossRefPubMedGoogle Scholar
  6. 6.
    Kraemer WJ, Ratamess NA. Fundamentals of resistance training: progression and exercise prescription. Med Sci Sports Exerc. 2004;36(4):674–88.CrossRefPubMedGoogle Scholar
  7. 7.
    Hackett DA, Johnson NA, Chow CM. Training practices and ergogenic aids used by male bodybuilders. J Strength Cond Res. 2013;27(6):1609–17.CrossRefPubMedGoogle Scholar
  8. 8.
    Arazi H, Asadi A. Effects of 8 weeks equal-volume resistance training with different workout frequency on maximal strength, endurance and body composition. Int J Sports Sci Eng. 2011;5(2):112–8.Google Scholar
  9. 9.
    Benton MJ, Kasper MJ, Raab SA, et al. Short-term effects of resistance training frequency on body composition and strength in middle-aged women. J Strength Cond Res. 2011;25(11):3142–9.CrossRefPubMedGoogle Scholar
  10. 10.
    Calder AW, Chilibeck PD, Webber CE, et al. Comparison of whole and split weight training routines in young women. Can J Appl Physiol. 1994;19(2):185–99.CrossRefPubMedGoogle Scholar
  11. 11.
    Candow DG, Burke DG. Effect of short-term equal-volume resistance training with different workout frequency on muscle mass and strength in untrained men and women. J Strength Cond Res. 2007;21(1):204–7.CrossRefPubMedGoogle Scholar
  12. 12.
    Carneiro NH, Ribeiro AS, Nascimento MA, et al. Effects of different resistance training frequencies on flexibility in older women. Clin Interv Aging. 2015;5(10):531–8.Google Scholar
  13. 13.
    Gentil P, Fischer B, Martorelli AS, et al. Effects of equal-volume resistance training performed one or two times a week in upper body muscle size and strength of untrained young men. J Sports Med Phys Fitness. 2015;55(3):144–9.PubMedGoogle Scholar
  14. 14.
    Lera Orsatti F, Nahas EA, Maesta N, et al. Effects of resistance training frequency on body composition and metabolics and inflammatory markers in overweight postmenopausal women. J Sports Med Phys Fitness. 2014;54(3):317–25.PubMedGoogle Scholar
  15. 15.
    McLester JR, Bishop P, Guilliams ME. Comparison of 1 day and 3 days per week of equal-volume resistance training in experienced subjects. J Strength Cond Res. 2000;14:273–81.Google Scholar
  16. 16.
    Ribeiro AS, Schoenfeld BJ, Silva DR, et al. Effect of two- versus three-way split resistance training routines on body composition and muscular strength in bodybuilders: A pilot study. Int J Sport Nutr Exerc Metab. 2015;25(6):559–65.CrossRefPubMedGoogle Scholar
  17. 17.
    Schoenfeld BJ, Ratamess NA, Peterson MD, et al. Influence of resistance training frequency on muscular adaptations in well-trained men. J Strength Cond Res. 2015;29(7):1821–9.CrossRefPubMedGoogle Scholar
  18. 18.
    Moher D, Liberati A, Tetzlaff J, PRISMA Group, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.CrossRefPubMedPubMedCentralGoogle Scholar
  19. 19.
    Greenhalgh T, Peacock R. Effectiveness and efficiency of search methods in systematic reviews of complex evidence: audit of primary sources. BMJ. 2005;331(7524):1064–5.CrossRefPubMedPubMedCentralGoogle Scholar
  20. 20.
    Brazzel-Roberts JV, Thomas LE. Effects of weight training frequency on the self-concept of college remales. J Appl Sports Sci Res. 1989;3(2):40–3.Google Scholar
  21. 21.
    Cooper H, Hedges L, Valentine J. The handbook of research synthesis and meta-analysis. 2nd ed. New York: Russell Sage Foundation; 2009.Google Scholar
  22. 22.
    Morris B. Estimating effect sizes from pretest-posttest-control group designs. Organ Res Meth. 2008;11(2):364–86.CrossRefGoogle Scholar
  23. 23.
    Borenstein M, Hedges LV, Higgins JPT. Effect sizes based on means. In: Introduction to meta-analysis. UK: John Wiley and Sons, LTD; 2009. p. 21–32.Google Scholar
  24. 24.
    Hedges LV, Tipton E, Johnson MC. Robust variance estimation in meta-regression with dependent effect size estimates. Res Synth Methods. 2010;1(1):39–65.CrossRefPubMedGoogle Scholar
  25. 25.
    Tipton E. Small sample adjustments for robust variance estimation with meta-regression. Psychol Methods. 2015;20(3):375–93.CrossRefPubMedGoogle Scholar
  26. 26.
    Wernbom M, Augustsson J, Thomee R. The influence of frequency, intensity, volume and mode of strength training on whole muscle cross-sectional area in humans. Sports Med. 2007;37(3):225–64.CrossRefPubMedGoogle Scholar
  27. 27.
    Guyatt GH, Oxman AD, Kunz R, et al. GRADE guidelines: 8. Rating the quality of evidence-indirectness. J Clin Epidemiol. 2011;64(12):1303–10.CrossRefPubMedGoogle Scholar
  28. 28.
    American College of Sports Medicine. American College of Sports Medicine position stand. Progression models in resistance training for healthy adults. Med Sci Sports Exerc. 2009;41(3):687–708.CrossRefGoogle Scholar
  29. 29.
    Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale: Lawrence Erlbaum; 1988.Google Scholar
  30. 30.
    Krieger JW. Single vs. multiple sets of resistance exercise for muscle hypertrophy: a meta-analysis. J Strength Cond Res. 2010;24(4):1150–9.CrossRefPubMedGoogle Scholar
  31. 31.
    Raastad T, Kirketeig A, Wolf D, et al. Powerlifters improved strength and muscular adaptations to a greater extent when equal total training volume was divided into 6 compared to 3 training sessions per week. 17th Annual Conference of the European College of Sport Science, Brugge, 2012.Google Scholar
  32. 32.
    Fry AC, Kraemer WJ, van Borselen F, et al. Performance decrements with high-intensity resistance exercise overtraining. Med Sci Sports Exerc. 1994;26(9):1165–73.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Brad J. Schoenfeld
    • 1
  • Dan Ogborn
    • 2
  • James W. Krieger
    • 3
  1. 1.Department of Health ScienceLehman CollegeBronxUSA
  2. 2.McMaster UniversityHamiltonCanada
  3. 3.Weightology, LLCIssaquahUSA

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