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Sports Medicine

, Volume 45, Issue 4, pp 577–585 | Cite as

Effect of Repetition Duration During Resistance Training on Muscle Hypertrophy: A Systematic Review and Meta-Analysis

  • Brad J. SchoenfeldEmail author
  • Dan I. Ogborn
  • James W. Krieger
Systematic Review

Abstract

Background

Maximizing the hypertrophic response to resistance training (RT) is thought to be best achieved by proper manipulation of exercise program variables including exercise selection, exercise order, length of rest intervals, intensity of maximal load, and training volume. An often overlooked variable that also may impact muscle growth is repetition duration. Duration amounts to the sum total of the concentric, eccentric, and isometric components of a repetition, and is predicated on the tempo at which the repetition is performed.

Objective

We conducted a systematic review and meta-analysis to determine whether alterations in repetition duration can amplify the hypertrophic response to RT.

Methods

Studies were deemed eligible for inclusion if they met the following criteria: (1) were an experimental trial published in an English-language refereed journal; (2) directly compared different training tempos in dynamic exercise using both concentric and eccentric repetitions; (3) measured morphologic changes via biopsy, imaging, and/or densitometry; (4) had a minimum duration of 6 weeks; (5) carried out training to muscle failure, defined as the inability to complete another concentric repetition while maintaining proper form; and (6) used human subjects who did not have a chronic disease or injury. A total of eight studies were identified that investigated repetition duration in accordance with the criteria outlined.

Results

Results indicate that hypertrophic outcomes are similar when training with repetition durations ranging from 0.5 to 8 s.

Conclusions

From a practical standpoint it would seem that a fairly wide range of repetition durations can be employed if the primary goal is to maximize muscle growth. Findings suggest that training at volitionally very slow durations (>10s per repetition) is inferior from a hypertrophy standpoint, although a lack of controlled studies on the topic makes it difficult to draw definitive conclusions.

Keywords

Resistance Training Muscle Hypertrophy Muscle Thickness Repetition Maximum Hypertrophic Response 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

This study was not funded by an outside source. The authors report no conflicts of interest for this study.

Conflict of interest

None.

References

  1. 1.
    Schoenfeld BJ. The mechanisms of muscle hypertrophy and their application to resistance training. J Strength Cond Res. 2010;24(10):2857–72.CrossRefPubMedGoogle Scholar
  2. 2.
    Petrella JK, Kim J, Mayhew DL, et al. Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysis. J Appl Physiol. 2008;104(6):1736–42.CrossRefPubMedGoogle Scholar
  3. 3.
    Kraemer WJ, Ratamess NA. Fundamentals of resistance training: progression and exercise prescription. Med Sci Sports Exerc. 2004;36(4):674–88.CrossRefPubMedGoogle Scholar
  4. 4.
    Headley SA, Henry K, Nindl BC, et al. Effects of lifting tempo on one repetition maximum and hormonal responses to a bench press protocol. J Strength Cond Res. 2011;25(2):406–13.CrossRefPubMedGoogle Scholar
  5. 5.
    Mookerjee S, Ratamess N. Comparison of strength differences and joint action durations between full and partial range-of-motion bench press exercise. J Strength Cond Res. 1999;13:76–81.Google Scholar
  6. 6.
    Bamman MM, Shipp JR, Jiang J, et al. Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans. Am J Physiol Endocrinol Metab. 2001;280(3):E383–90.PubMedGoogle Scholar
  7. 7.
    Westcott WL, Winett RA, Anderson ES, et al. Effects of regular and slow speed resistance training on muscle strength. J Sports Med Phys Fitness. 2001;41(2):154–8.PubMedGoogle Scholar
  8. 8.
    Greenhalgh T, Peacock R. Effectiveness and efficiency of search methods in systematic reviews of complex evidence: audit of primary sources. BMJ. 2005;331(7524):1064–5.CrossRefPubMedCentralPubMedGoogle Scholar
  9. 9.
    Nogueira W, Gentil P, Mello SN, et al. Effects of power training on muscle thickness of older men. Int J Sports Med. 2009;30(3):200–4.CrossRefPubMedGoogle Scholar
  10. 10.
    Watanabe Y, Madarame H, Ogasawara R, et al. Effect of very low-intensity resistance training with slow movement on muscle size and strength in healthy older adults. Clin Physiol Funct Imaging. 2014;34(6):463–70.CrossRefPubMedGoogle Scholar
  11. 11.
    Watanabe Y, Tanimoto M, Ohgane A, et al. Increased muscle size and strength from slow-movement, low-intensity resistance exercise and tonic force generation. J Aging Phys Act. 2013;21(1):71–84.PubMedGoogle Scholar
  12. 12.
    Munn J, Herbert RD, Hancock MJ, et al. Resistance training for strength: effect of number of sets and contraction speed. Med Sci Sports Exerc. 2005;37(9):1622–6.CrossRefPubMedGoogle Scholar
  13. 13.
    Schuenke MD, Herman JR, Gliders RM, et al. Early-phase muscular adaptations in response to slow-speed versus traditional resistance-training regimens. Eur J Appl Physiol. 2012;112(10):3585–95.CrossRefPubMedGoogle Scholar
  14. 14.
    Rana SR, Chleboun GS, Gilders RM, et al. Comparison of early phase adaptations for traditional strength and endurance, and low velocity resistance training programs in college-aged women. J Strength Cond Res. 2008;22(1):119–27.CrossRefPubMedGoogle Scholar
  15. 15.
    Cooper H, Hedges L, Valentine J. The handbook of research synthesis and meta-analysis. 2nd ed. New York: Russell Sage Foundation; 2009.Google Scholar
  16. 16.
    Morris SB, DeShon RP. Combining effect size estimates in meta-analysis with repeated measures and independent-groups designs. Psychol Methods. 2002;7(1):105–25.CrossRefPubMedGoogle Scholar
  17. 17.
    Hox JJ, de Leeuw ED. Multilevel models for meta-analysis. In: Reise SP, Duan N, editors. Multilevel modeling. Methodological advances, issues, and applications, Mahway: Lawrence Erlbaum Associates; 2003. pp. 90–111.Google Scholar
  18. 18.
    Thompson SG, Sharp SJ. Explaining heterogeneity in meta-analysis: a comparison of methods. Stat Med. 1999;18(20):2693–708.CrossRefPubMedGoogle Scholar
  19. 19.
    Berkey CS, Hoaglin DC, Mosteller F, et al. A random-effects regression model for meta-analysis. Stat Med. 1995;14(4):395–411.CrossRefPubMedGoogle Scholar
  20. 20.
    Hochberg Y. A sharper bonferroni procedure for multiple tests of significance. Biometrika. 1988;75:800–2.CrossRefGoogle Scholar
  21. 21.
    Levine JA, Abboud L, Barry M, et al. Measuring leg muscle and fat mass in humans: comparison of CT and dual-energy X-ray absorptiometry. J Appl Physiol. 2000;88(2):452–6.PubMedGoogle Scholar
  22. 22.
    Keogh JWL, Wilson GJ, Weatherby RP. A cross-sectional comparison of different resistance training techniques in the bench press. J Strength Cond Res. 1999;13:247–58.Google Scholar
  23. 23.
    Tanimoto M, Sanada K, Yamamoto K, et al. Effects of whole-body low-intensity resistance training with slow movement and tonic force generation on muscular size and strength in young men. J Strength Cond Res. 2008;22(6):1926–38.CrossRefPubMedGoogle Scholar
  24. 24.
    Tanimoto M, Ishii N. Effects of low-intensity resistance exercise with slow movement and tonic force generation on muscular function in young men. J Appl Physiol. 2006;100(4):1150–7.CrossRefPubMedGoogle Scholar
  25. 25.
    Young WB, Bilby GE. The effect of voluntary effort to influence speed of contraction on strength, muscular power, and hypertrophy development. J Strength Cond Res. 1993;7(3):172–8.Google Scholar
  26. 26.
    Claflin DR, Larkin LM, Cederna PS, et al. Effects of high- and low-velocity resistance training on the contractile properties of skeletal muscle fibers from young and older humans. J Appl Physiol (1985). 2011;111(4):1021–30.Google Scholar
  27. 27.
    Keeler LK, Finkelstein LH, Miller W, et al. Early-phase adaptations of traditional-speed vs. superslow resistance training on strength and aerobic capacity in sedentary individuals. J Strength Cond Res. 2001;15(3):309–14.PubMedGoogle Scholar
  28. 28.
    Neils CM, Udermann BE, Brice GA, et al. Influence of contraction velocity in untrained individuals over the initial early phase of resistance training. J Strength Cond Res. 2005;19(4):883–7.PubMedGoogle Scholar
  29. 29.
    Shepstone TN, Tang JE, Dallaire S, et al. Short-term high- vs. low-velocity isokinetic lengthening training results in greater hypertrophy of the elbow flexors in young men. J Appl Physiol (1985). 2005;98(5):1768–76.Google Scholar
  30. 30.
    Farthing JP, Chilibeck PD. The effects of eccentric and concentric training at different velocities on muscle hypertrophy. Eur J Appl Physiol. 2003;89(6):578–86.CrossRefPubMedGoogle Scholar
  31. 31.
    Gillies EM, Putman CT, Bell GJ. The effect of varying the time of concentric and eccentric muscle actions during resistance training on skeletal muscle adaptations in women. Eur J Appl Physiol. 2006;97(4):443–53.CrossRefPubMedGoogle Scholar
  32. 32.
    Mitchell CJ, Churchward-Venne TA, West DD, et al. Resistance exercise load does not determine training-mediated hypertrophic gains in young men. J Appl Physiol. 2012;113:71–7.CrossRefPubMedCentralPubMedGoogle Scholar
  33. 33.
    Ogasawara R, Loenneke JP, Thiebaud RS, et al. Low-load bench press training to fatigue results in muscle hypertrophy similar to high-load bench press training. Int J Clin Med. 2013;4:114–21.CrossRefGoogle Scholar
  34. 34.
    Adam A, De Luca CJ. Recruitment order of motor units in human vastus lateralis muscle is maintained during fatiguing contractions. J Neurophysiol. 2003;90(5):2919–27.CrossRefPubMedGoogle Scholar
  35. 35.
    Alway SE, MacDougall JD, Sale DG, et al. Functional and structural adaptations in skeletal muscle of trained athletes. J Appl Physiol (1985). 1988;64(3):1114–20.Google Scholar
  36. 36.
    Sale DG, MacDougall JD, Alway SE, et al. Voluntary strength and muscle characteristics in untrained men and women and male bodybuilders. J Appl Physiol (1985). 1987;62(5):1786–93.Google Scholar
  37. 37.
    Sale DG, Upton AR, McComas AJ, et al. Neuromuscular function in weight-trainers. Exp Neurol. 1983;82(3):521–31.CrossRefPubMedGoogle Scholar
  38. 38.
    Huczel HA, Clarke DH. A comparison of strength and muscle endurance in strength-trained and untrained women. Eur J Appl Physiol Occup Physiol. 1992;64(5):467–70.CrossRefPubMedGoogle Scholar
  39. 39.
    Maughan RJ, Watson JS, Weir J. Muscle strength and cross-sectional area in man: a comparison of strength-trained and untrained subjects. Br J Sports Med. 1984;18(3):149–57.CrossRefPubMedCentralPubMedGoogle Scholar
  40. 40.
    Wilkinson SB, Phillips SM, Atherton PJ, et al. Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle. J Physiol. 2008;586(Pt 15):3701–17.CrossRefPubMedCentralPubMedGoogle Scholar
  41. 41.
    Tang JE, Perco JG, Moore DR, et al. Resistance training alters the response of fed state mixed muscle protein synthesis in young men. Am J Physiol Regul Integr Comp Physiol. 2008;294(1):R172–8.CrossRefPubMedGoogle Scholar
  42. 42.
    Phillips SM, Tipton KD, Ferrando AA, et al. Resistance training reduces the acute exercise-induced increase in muscle protein turnover. Am J Physiol. 1999;276(1 Pt 1):E118–24.PubMedGoogle Scholar
  43. 43.
    Gordon PM, Liu D, Sartor MA, et al. Resistance exercise training influences skeletal muscle immune activation: a microarray analysis. J Appl Physiol (1985). 2012;112(3):443–53.Google Scholar

Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Brad J. Schoenfeld
    • 1
    Email author
  • Dan I. Ogborn
    • 2
  • James W. Krieger
    • 3
  1. 1.Department of Health ScienceLehman CollegeBronxUSA
  2. 2.McMaster UniversityHamiltonCanada
  3. 3.Weightology, LLCIssaquahUSA

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