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Pohl D, et al. Multicentre, non-interventional study of the efficacy and tolerability of linaclotide in the treatment of irritable bowel syndrome with constipation in primary, secondary and tertiary centres: The Alpine study. BMJ Open 9: No. 12, Dec 2019. Available from: URL: http://doi.org/10.1136/bmjopen-2018-025627