Reactions Weekly

, Volume 1781, Issue 1, pp 50–50 | Cite as


Catheter-related bloodstream infections due to O. anthropi: 4 case reports
Case report
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An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

A case series described four patients (2 men and 2 women) aged 55−71 years, who developed catheter-related bloodstream infections due to O. anthropi following treatment with bevacizumab, folinic acid, fluorouracil and irinotecan (1 patient), doxorubicin, ifosfamide and dacarbazine (1 patient), bevacizumab, cetuximab, folinic acid, fluorouracil, irinotecan and oxaliplatin (1 patient) or etoposide, doxorubicin, cisplatin and mitotane (1 patient) for malignancies [routes and dosages not stated].

Case 1: A 71-year-old man started receiving folinic acid, fluorouracil and irinotecan (FOLFIRI regimen involving irinotecan at 25% reduced dose) alongside bevacizumab in November 2016 for colorectal cancer with lung, hepatic and lymph node metastases. Folinic acid, fluorouracil and...


  1. Caroleo B, et al. Catheter-related bloodstream infections: A root cause analysis in a series of simultaneous Ochrobactrum anthropi infections. Current Pharmaceutical Biotechnology 20: 609-614, No. 8, 2019. Available from: URL: - ItalyCrossRefGoogle Scholar

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© Springer International Publishing AG 2019

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