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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
A case series described a 69-year-old woman and a 58-year-old woman, who developed anaphylactic shock following administration of indocyanine green (a fluorescent dye) for video angiography monitoring during a cerebrovascular surgery in South Korea. Additionally, the 69-year-old woman exhibited lack of efficacy to atropine, epinephrine and phenylephrine for life-threatening hypotension during the anaphylactic shock [not all dosages and routes stated].
Patient 1: A 69-year-old woman, who had an unruptured intracranial aneurysm (IA), at the origin of the posterior communicating artery, underwent craniotomy and clipping of the IA. During the surgery, she received various medications. After uneventful surgical exposure and initial aneurysm clip placement, she received indocyanine...