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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
A 16-year-old girl exhibited masking of anaplastic large cell lymphoma during treatment with celecoxib, ibuprofen, ketorolac and paracetamol for abdominal pain and prednisone for presumed allergic reaction [dosages and duration of treatments to reaction onset not stated; not all routes stated].
The girl presented to an emergency department with abdominal pain for 5 weeks and intermittent fevers. Her abdominal pain was relieved by unspecified NSAIDs and paracetamol [acetaminophen]. She reported an enlarged, tender right sided cervical lymph node that appeared 2−3 months prior to the presentation. Her medical history included Lyme disease with Bell's palsy 2 years prior which was appropriately treated. She reported intermittent joint pain and muscle aches since then. She had...
- Penberthy K, et al. Abdominal pain and intermittent fevers in a 16-year-old girl. Pediatrics 144: No. 3, Sep 2019. Available from: URL: http://doi.org/10.1542/peds.2019-0093 - USA