Multiple drug overdose
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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
* Drug overdose
A case series described a 24-year-old woman and a 65-year-old man, who experienced various toxicities secondary to multiple drug overdose in an attempt of suicide [not all quantities stated]. Additionally, these patients exhibited lack of drug effect with sodium chloride, norepinephrine, epinephrine, glucagon, hydrocortisone sodium succinate, hyperinsulinemia euglycemia, vasopressin or Angiotensin-II.
Case 1: A 24-year-old woman with known hypertension and dilated cardiomyopathy was found at home approximately 2 hours following an intentional ingestion of her prescribed medications in an attempt of suicide. Her medications comprised amlodipine, aspirin, carvedilol, furosemide, hydralazine, isosorbide mononitrate, lisinopril and spironolactone. Her medications lay...
- Carpenter JE, et al. Successful Treatment of Antihypertensive Overdose Using Intravenous Angiotensin II. Journal of Emergency Medicine 57: 339-344, No. 3, Sep 2019. Available from: URL: http://doi.org/10.1016/j.jemermed.2019.05.027 - Georgia