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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
A 66-year-old man developed herpes zoster, cutaneous small vessel vasculitis, Pseudomonas infection, Enterococcus infection, Escherichia coli infection and Stenotrophomonas maltophila infection during treatment with methotrexate and prednisone for multisystem sarcoidosis [durations of treatments to reactions onsets not stated].
The man had a 6-year history of multisystem sarcoidosis, chronic kidney disease and hypertension. He presented to an emergency department (ED) with increasing left leg pain and left lower extremity ulcerations. Ten months previously, he started developing red papules on the left lower leg. At that time, he was asymptomatic. Six months later, the lesions begun to ulcerate. A biopsy was consistent with cutaneous sarcoidosis. He was receiving...
- Clark AK, et al. Herpes zoster presenting as unilateral vasculitis. Dermatology Online Journal 24: 10, No. 11, Nov 2018. Available from: URL: https://escholarship.org/uc/item/5dd717sw - USA