Reactions Weekly

, Volume 1734, Issue 1, pp 349–349 | Cite as

Multiple drugs

Various toxicities: 9 case reports
Case report
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An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

  • * Drug overdose

In a study of 42 patients, nine adult men (aged 28−53 years) were described, who developed various toxicities due to drug overdose or drug toxicity following administration of alprazolam, codeine, diphenhydramine, fentanyl, fluoxetine, metamfetamine, morphine or quetiapine. Eventually, all men died secondary to drug toxicity/intoxication or accidental drug overdose [indications, dosages, routes and durations of administrations to reactions onset not stated].

Case 11: A 52-year-old man was found dead in residence. He had a history of illicit drug use. Needles were located at the scene. Toxicology findings of peripheral blood showed para-fluoro isobutyryl fentanyl level of 18 ng/mL, morphine level of 73 ng/mL, fluoxetine level of 63 ng/mL, norfluoxetine level of...


  1. Fogarty MF, et al. Analysis of Fentanyl and 18 Novel Fentanyl Analogs and Metabolites by LC-MS-MS, and report of Fatalities Associated with Methoxyacetylfentanyl and Cyclopropylfentanyl. Journal of Analytical Toxicology 42: 592-604, No. 9, Nov 2018. Available from: URL: - USA

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