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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
A 44-year-old woman postoperatively developed severe constipation complicated by fecal impaction and functional bowel obstruction leading to poor oral intake, thereby causing starvation ketoacidosis and non-pancreatitis lipase elevation. Additionally, she developed high anion gap metabolic acidosis secondary to starvation ketoacidosis.
The woman, who was non-diabetic and had morbid obesity, was admitted with a 2-week history of poor oral tolerance and severe constipation as well as 1 day history of nausea and vomiting. Two weeks prior to the admission, she had undergone an uneventful bariatric surgery with laparoscopic sleeve gastrectomy for morbid obesity. Postoperatively, she received pain management with oral hydromorphone 2mg every 4 hours as needed until 5 days prior to the...
- Song R, et al. Post-bariatric surgery starvation ketoacidosis and lipase elevation in the absence of DKA or pancreatitis. American Journal of Emergency Medicine 36: 525.e3-525.e5, No. 3, Mar 2018. Available from: URL: http://doi.org/10.1016/j.ajem.2017.10.068 - China