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, Volume 1731, Issue 1, pp 156–156 | Cite as

Leflunomide

Neovascularisation in bladder and thrombocytopenia with associated complications: case report
Case report
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An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

A 70-year-old woman developed haematuria, normochromic normocytic anaemia, thrombocytopenia and neovascularisation in bladder during treatment with leflunomide for seropositive rheumatoid arthritis [route and dosage not stated].

The woman presented with a 5-day history of painless gross haematuria with some difficulty in micturition. As a result, she was admitted to a urology unit. She had normochromic normocytic anaemia (haemoglobin level: 11.4 g/dL), hypertension and rheumatoid arthritis. She was on leflunomide, prednisolone, sulfasalazine and monthly injection of golimumab for seropositive rheumatoid arthritis. She did not have dysuria, fever, abdominal and flank pain. Four months prior to the current presentation, she had experienced a similar episode for a duration of...

References

  1. Khor V, et al. The mysterious gross haematuria in patient on Leflunomide: A case report and literature review. Urology Case Reports 22: 44-46, Jan 2019. Available from: URL: https://doi.org/10.1016/j.eucr.2018.10.012
  2. Khor V, et al. The mystery of gross haematuria in patient on leflunomide: A case report and literature review. BJU International 122 (Suppl. 1): 17-18 abstr. C-10066, Jul 2018. Available from: URL: https://onlinelibrary.wiley.com/doi/full/10.1111/bju.14430
  3. Khor V, et al. The mystery of gross haematuria in a patient on leflunomide: A case report and literature review. Arab Journal of Urology 16 (Suppl. 1): S30 abstr. 62, Nov 2018. Available from: URL: http://doi.org/10.1016/j.aju.2018.10.015

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© Springer Nature Switzerland AG 2018

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