Monosodium phosphate/disodium phosphate
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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
In a case report, five patients (3 women and 2 men) aged 62−86 years were described, who developed phosphate nephropathy following the administration of monosodium phosphate/disodium phosphate [Fosfosoda] during colonoscopy [dosage not stated].
Case 1: A 72-year-old man developed phosphate nephropathy following the administration of monosodium phosphate/disodium phosphate. The man was referred to the nephrology department after elevation was noted in his plasma creatinine at 6.2 mg/dL (baseline 1.2 mg/dL), uric acid of 10.5 mg/dL and phosphorous of 5.6 mg/dL. His medical history was significant for arterial hypertension (under treatment with olmesartan and hydrochlorothiazide) and prostate surgery. Additionally, he was receiving unspecified NSAIDs. One month prior to the...
- Garcia LC, et al. "Hidden" nephropathy after oral phosphate preparation to colonoscopy. Nefrologia 38: 442-443, No. 4, Jul-Aug 2018. Available from: URL: http://doi.org/10.1016/j.nefroe.2017.08.002 - Spain