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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
In a case series 4 women aged 22−29 years were described, of whom two women developed uterine rupture following treatment with misoprostol and oxytocin for induction of labour, and other two women developed uterine rupture following treatment with oxytocin for induction of labour [routes not stated; not all dosages stated].
Case 1: The 29-year-old gravida 3, para 2 woman presented at 41 weeks of gestation with hypotension and tachycardia following forceps application. She received treatment with misoprostol followed by augmentation with oxytocin for induction of labour, and forceps delivery was attempted for fetal distress in the second stage of labour. Examination revealed BP of 82/62mm Hg, severe degree of pallor with pulse rate of 118 beats/minute and generalised tenderness...
- Dubey S, et al. Unexpected uterine rupture: A case series and review of literature. Journal of Clinical and Diagnostic Research 12: QR01-QR03, No. 7, Jul 2018. Available from: URL: http://www.jcdr.net/pdf_download.asp?issn=&year=2018&month=July&volume=12&issue=7&page=RC01&id=11750 - India