PharmacoEconomics

, Volume 31, Issue 11, pp 991–1003 | Cite as

Methods to Elicit Probability Distributions from Experts: A Systematic Review of Reported Practice in Health Technology Assessment

  • Bogdan Grigore
  • Jaime Peters
  • Christopher Hyde
  • Ken Stein
Systematic Review

Abstract

Background

Elicitation is a technique that can be used to obtain probability distribution from experts about unknown quantities. We conducted a methodology review of reports where probability distributions had been elicited from experts to be used in model-based health technology assessments.

Methods

Databases including MEDLINE, EMBASE and the CRD database were searched from inception to April 2013. Reference lists were checked and citation mapping was also used. Studies describing their approach to the elicitation of probability distributions were included. Data was abstracted on pre-defined aspects of the elicitation technique. Reports were critically appraised on their consideration of the validity, reliability and feasibility of the elicitation exercise.

Results

Fourteen articles were included. Across these studies, the most marked features were heterogeneity in elicitation approach and failure to report key aspects of the elicitation method. The most frequently used approaches to elicitation were the histogram technique and the bisection method. Only three papers explicitly considered the validity, reliability and feasibility of the elicitation exercises.

Conclusion

Judged by the studies identified in the review, reports of expert elicitation are insufficient in detail and this impacts on the perceived usability of expert-elicited probability distributions. In this context, the wider credibility of elicitation will only be improved by better reporting and greater standardisation of approach. Until then, the advantage of eliciting probability distributions from experts may be lost.

Supplementary material

40273_2013_92_MOESM1_ESM.doc (23 kb)
Supplementary material (DOC 23 kb)

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Copyright information

© Springer International Publishing Switzerland 2013

Authors and Affiliations

  • Bogdan Grigore
    • 1
  • Jaime Peters
    • 1
  • Christopher Hyde
    • 1
  • Ken Stein
    • 1
  1. 1.Peninsula Technology Assessment Group (PenTAG), Institute of Health Research, University of Exeter Medical SchoolUniversity of ExeterExeterUK

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