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Pediatric Drugs

, Volume 15, Issue 6, pp 493–503 | Cite as

Cutaneous Drug Reactions in Children: An Update

  • Kara HeelanEmail author
  • Neil H. Shear
Review Article

Abstract

Cutaneous drug reactions account for a large proportion of adverse drug reactions. Cutaneous drug reactions can be very challenging to diagnose. They can mimic many other skin diseases; this is especially evident during childhood, when viral exanthems are commonplace. Also, if a patient is taking numerous medications, establishing causality to a specific drug can be multifaceted and difficult. The purpose of this review is to highlight an approach to the diagnosis of a suspected cutaneous drug reaction in a child. We have classified different types of drug eruptions by morphology: exanthematous, urticarial, pustular, and bullous. Within each of these groups we have divided them into simple, benign, or non-febrile and complex or febrile reactions. We also include a miscellaneous group to ensure a methodical review.

Keywords

Juvenile Idiopathic Arthritis Toxic Epidermal Necrolysis Cefaclor Bullous Pemphigoid Insulin Detemir 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

No sources of funding were used to prepare this review. Kara Heelan has received fellowship support from Abbott (AbbVie). Neil H. Shear has no conflicts of interest that are directly relevant to the content of this review.

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Copyright information

© Springer International Publishing Switzerland 2013

Authors and Affiliations

  1. 1.Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences CentreUniversity of TorontoTorontoCanada
  2. 2.Division of Clinical Pharmacology & Toxicology, Department of Medicine, Sunnybrook Health Sciences CentreUniversity of TorontoTorontoCanada

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