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The Patient - Patient-Centered Outcomes Research

, Volume 6, Issue 4, pp 241–255 | Cite as

Assessing Patient Preferences for Treatment Options and Process of Care in Inflammatory Bowel Disease: A Critical Review of Quantitative Data

  • Meenakshi BewtraEmail author
  • F. Reed Johnson
Review Article

Abstract

Inflammatory bowel disease (IBD), consisting of both Crohn’s disease (CD) and ulcerative colitis (UC), are chronic inflammatory conditions of the intestinal tract. As there is no cure for either CD or UC, patients with these conditions face numerous treatment decisions regarding their disease. The aim of this review is to evaluate literature regarding quantitative studies of patient preferences in therapy for IBD with a focus on the emerging technique of stated preference and its application in IBD. Numerous simple survey-based studies have been performed evaluating IBD patients’ preferences for medication frequency, mode of delivery, potential adverse events, etc., as well as variations in these preferences. These studies are limited, however, as they are purely descriptive in nature with limited quantitative information on the relative value of treatment alternatives. Time trade-off and standard-gamble studies have also been utilized to quantify patient utility for various treatment options or outcomes. However, these types of studies suffer from inaccurate assumptions regarding patient choice behavior. Stated preference is an emerging robust methodology increasingly utilized in health care that can determine the relative utility for a therapy option as well as its specific attributes (such as efficacy or adverse side effects). Stated preference techniques have begun to be applied in IBD and offer an innovative way of examining the numerous therapy options these patients and their providers face.

Keywords

Inflammatory Bowel Disease Ulcerative Colitis Progressive Multifocal Leukoencephalopathy Inflammatory Bowel Disease Patient Natalizumab 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

Funding for this study came, in part, from NIH K08 DK084347-01.

Meenakshi Bewtra conducted the literature search and summarized the findings. Meenakshi Bewtra and F. Reed Johnson interpreted the findings and developed the manuscript.

Meenakshi Bewtra has received a research grant from Centocor. F. Reed Johnson declares no conflicts of interest.

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Copyright information

© Springer International Publishing Switzerland 2013

Authors and Affiliations

  1. 1.Department of GastroenterologyUniversity of PennsylvaniaPhiladelphiaUSA
  2. 2.Center for Clinical Epidemiology and BiostatisticsUniversity of PennsylvaniaPhiladelphiaUSA
  3. 3.RTI-HS, Research Triangle InstituteResearch Triangle ParkUSA

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