Probiotics could pay off in Helicobacter pylori eradication

  • Ahmed G. AbdelhamidEmail author


Helicobacter pylori infection, a cause of gastric disease, is generally eradicated with standard antibiotic therapy. However, adding probiotics to standard therapy may improve rates of eradication and adverse effects. Despite the growing interest in probiotics in this area, data should be carefully interpreted before evidence-driven decision-making in clinical settings can be made. This commentary highlights current standard therapy, and the efficacy and underlying mechanisms of probiotics in H. pylori eradication. The commentary also speculates on some controversies around research results, and gives an opinion on design of probiotic formulations aided by emerging whole genome sequencing tools.


Compliance with ethical standards

Conflict of interest

The author declares no competing interests.


Not applicable.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Food Science and TechnologyThe Ohio State UniversityColumbusUSA
  2. 2.Faculty of ScienceBenha UniversityBenhaEgypt

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