Probiotics could pay off in Helicobacter pylori eradication
- 22 Downloads
Helicobacter pylori infection, a cause of gastric disease, is generally eradicated with standard antibiotic therapy. However, adding probiotics to standard therapy may improve rates of eradication and adverse effects. Despite the growing interest in probiotics in this area, data should be carefully interpreted before evidence-driven decision-making in clinical settings can be made. This commentary highlights current standard therapy, and the efficacy and underlying mechanisms of probiotics in H. pylori eradication. The commentary also speculates on some controversies around research results, and gives an opinion on design of probiotic formulations aided by emerging whole genome sequencing tools.
Compliance with ethical standards
Conflict of interest
The author declares no competing interests.
- 4.Oleastro M, Ménard A. The role of Helicobacter pylori outer membrane proteins in adherence and pathogenesis. Biology (Basel). 2013;2(3):1110–34.Google Scholar