Base the pharmacological treatment of post-stroke muscle spasticity on the needs and preferences of the patient
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The pharmacological treatment of post-stroke muscle spasticity should be individualized according to several factors, including treatment objectives and the patient’s preferences. Botulinum neurotoxin is the first-line treatment, with peripheral nerve blocks being an option for spasticity of the proximal lower limb muscles. The use of oral muscle relaxants should be limited, as they are associated with the risk of generalized weakness and systemic adverse effects.