Drugs & Aging

, Volume 30, Issue 11, pp 871–876

Management of Inflammatory Bowel Disease in the Elderly: Do Biologicals Offer A Better Alternative?

Current Opinion


The management of inflammatory bowel disease (IBD) in elderly patients provides added complexity for healthcare providers who need to take into account the high likelihood of co-morbid disease, the need for polypharmacy and, in many instances, greater patient fragility. While biologics are often considered first-line corticosteroid-sparing strategies for moderate to severe disease, the additional variables unique to an elderly patient warrant consideration when discussing IBD therapeutics. As chronic corticosteroid use, although relatively common among older IBD patients, is suboptimal, the efficacy and safety of biologics compared with immunomodulators among older IBD patients needs additional investigation.


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Copyright information

© Springer International Publishing Switzerland 2013

Authors and Affiliations

  1. 1.Division of Digestive DiseasesDavid Geffen School of Medicine at UCLALos AngelesUSA
  2. 2.Division of GastroenterologyNYU Langone Medical CenterNew YorkUSA

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