Drugs

, Volume 78, Issue 1, pp 153–154 | Cite as

Correction to: Opicapone: A Review in Parkinson’s Disease

Correction
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1 Correction to: Drugs (2016) 76:1293–1300  https://doi.org/10.1007/s40265-016-0623-y

Page 1293, column 2, section 1, paragraph 1, lines 1-3: the following sentence, which previously read:

Parkinson’s disease (PD) is the most common chronic, progressive, neurodegenerative disease, with a mean age of onset of 57 years [1, 2].

Should read:

Parkinson’s disease (PD) is the second most common chronic, progressive, neurodegenerative disease, with a mean age of onset of 57 years [1, 2].

Page 1294, column 1, paragraph 2, lines 1-6: the following sentence, which previously read:

Only a small fraction of an administered L-Dopa dose crosses the BBB, reflecting the extensive distribution of L-Dopa and its rapid peripheral metabolism by aromatic L-amino acid decarboxylase to dopamine and by catechol-O-methyltransferase (COMT) to 3 O-methyldopa (3-OMD) [1–3].

Should read:

Only a small fraction of an administered L-Dopa dose crosses the BBB, reflecting the extensive distribution of L-Dopa and its rapid peripheral metabolism by aromatic L-amino acid decarboxylase to dopamine and by catechol-O-methyltransferase (COMT) to 3 O-methyldopa (3-OMD) [2, 3].

Page 1296, column 1, paragraph 2, lines 1-6: the following sentence, which previously read:

Significantly (p ≤ 0.009) more opicapone 50 mg/day than placebo or entacapone recipients experienced improvements (i.e. minimally improved to very much improved ratings) from baseline in scores for Clinician’s Global Impression of Change (PGI-C) and Patient’s Global Impression of Change (PGI-C) [16].

Should read:

Significantly (p ≤ 0.009) more opicapone 50 mg/day than placebo or entacapone recipients experienced improvements (i.e. minimally improved to very much improved ratings) from baseline in scores for Clinician’s Global Impression of Change (CGI-C) and Patient’s Global Impression of Change (PGI-C) [16].

Page 1299, column 2, paragraph 1, lines 1-6: the following text, which previously read:

administered three times daily [1–3]. Entacapone is also available as a fixed-dose L-Dopa/ carbidopa/entacapone tablet [40], thereby potentially improving compliance. Tolcapone is also associated with an increased risk of hepatotoxicity (albeit very rare), which limits its use to patients who fail to respond to other COMT inhibitors [1–3].

Should read:

administered three times daily [3]. Entacapone is also available as a fixed-dose L-Dopa/ carbidopa/entacapone tablet [40], thereby potentially improving compliance. Tolcapone is also associated with an increased risk of hepatotoxicity (albeit very rare), which limits its use to patients who fail to respond to other COMT inhibitors [3].

Page 1299 reference list: Reference 1, which previously read:

1. Samii A, Nutt J, Ransom RR, et al. Parkinson’s disease. Lancet. 2004;2004(362):1783–93

Should read:

1. Kalia LV, Lang AE. Parkinson’s disease. Lancet. 2015; (386):896-912

Copyright information

© Springer International Publishing AG, part of Springer Nature 2017

Authors and Affiliations

  1. 1.SpringerAucklandNew Zealand

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