Clinical Drug Investigation

, Volume 39, Issue 9, pp 899–908 | Cite as

Hypertension and Health-Related Quality of Life (HRQoL): Evidence from the US Hispanic Population

  • Elizabeth Riley
  • Jongwha ChangEmail author
  • Chanhyun Park
  • Sean Kim
  • Inho Song
Original Research Article


Background and Objective

Little evidence exists regarding the marginal decrease in health-related quality of life (HRQoL) in relation to the presence of hypertension among a Hispanic population based on US population-based research.


This cross-sectional study used data from the 2014 to 2015 Medical Expenditure Panel Survey (MEPS). The target population was comprised of Hispanic community-dwelling residents with hypertension in the USA. The independent variable was the presence of hypertension. The dependent variable was HRQoL, which was measured using the Short Form-12 (SF-12) physical health composite scale (PCS) and mental health composite scale (MCS).


A total of 13,933 members of the Hispanic population met the study inclusion criteria, and the estimated population size was 36,440,400 Hispanics. Among them, 82.9% did not have any hypertensive condition (n = 11,466), while 17.7% had some hypertensive condition (n = 2467). SF-12 PCS scores (95% CI) were 46.62 (45.68–47.57) in the Hispanic population with hypertension and 51.62 (51.1–52.14) in the Hispanic population without hypertension. SF-12 MCS scores (95% CI) were 52.67 (52.07–53.27) in patients without hypertension and 50.35 (49.45–51.26) in the Hispanic population with hypertensive conditions.


The presence of hypertension was associated with lower HRQoL in the Hispanic population. Based on our findings, we suggest that healthcare providers should monitor a hypertensive minority population for anxiety and mood disorders and recommend psychiatric assessment and treatment if appropriate.


Compliance with Ethical Standards

Conflict of interest

Elizabeth Riley, Chanhyun Park, Sean Kim, Inho Song, and Jongwha Chang declare no conflicts of interest.


This project was supported by a UTEP School of Pharmacy Seed Grant (226811487A).

Ethics approval

Institutional Review Board (IRB) approval was waived since MEPS is a publicly available de-identified dataset.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Elizabeth Riley
    • 1
  • Jongwha Chang
    • 1
    Email author
  • Chanhyun Park
    • 2
  • Sean Kim
    • 3
  • Inho Song
    • 4
  1. 1.Department of Pharmacy Practice, School of PharmacyUniversity of Texas at El PasoEl PasoUSA
  2. 2.School of PharmacyNortheastern UniversityBostonUSA
  3. 3.School of PharmacyShenandoah UniversityWinchesterUSA
  4. 4.Korea Development InstituteSejongSouth Korea

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