American Journal of Clinical Dermatology

, Volume 19, Issue 2, pp 223–235 | Cite as

Vitamin D and the Skin: An Update for Dermatologists

  • Elio Kechichian
  • Khaled EzzedineEmail author
Review Article


Vitamin D plays a key role in skeletal and cardiovascular disorders, cancers, central nervous system diseases, reproductive diseases, infections, and autoimmune and dermatological disorders. The two main sources of vitamin D are sun exposure and oral intake, including vitamin D supplementation and dietary intake. Multiple factors are linked to vitamin D status, such as Fitzpatrick skin type, sex, body mass index, physical activity, alcohol intake, and vitamin D receptor polymorphisms. Patients with photosensitive disorders tend to avoid sun exposure, and this practice, along with photoprotection, can put this category of patients at risk for vitamin D deficiency. Maintaining a vitamin D serum concentration within normal levels is warranted in atopic dermatitis, psoriasis, vitiligo, polymorphous light eruption, mycosis fungoides, alopecia areata, systemic lupus erythematosus, and melanoma patients. The potential determinants of vitamin D status, as well as the benefits and risks of vitamin D (with a special focus on the skin), will be discussed in this article.


Compliance with Ethical Standards

Conflict of interest

Elio Kechichian and Khaled Ezzedine have no conflicts of interest to declare.


No funding was received for the preparation of this review.


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of DermatologyHôpital Henri MondorCréteilFrance
  2. 2.Faculty of MedicineSaint Joseph UniversityBeirutLebanon
  3. 3.EA EpiDermE (Epidémiologie en Dermatologie et Evaluation des Thérapeutiques)UPEC-Université Paris-Est CréteilCréteilFrance

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