Journal of Diabetes & Metabolic Disorders

, Volume 18, Issue 1, pp 119–125 | Cite as

Effects of ginger supplementation on anthropometric, glycemic and metabolic parameters in subjects with metabolic syndrome: A randomized, double-blind, placebo-controlled study

  • Mehran Rahimlou
  • Zahra Yari
  • Elham Rayyani
  • Seyed Ali Keshavarz
  • Seyedahmad Hosseini
  • Nava Morshedzadeh
  • Azita HekmatdoostEmail author
Research Article



Metabolic syndrome (MetS) is one of the worldwide most chronic endocrine disorders. The disease can also lead to several other chronic disorders such as type 2 diabetes mellitus, cardiovascular diseases, renal diseases and cancers. This study aimed to evaluate the safety and efficacy of ginger powder on biochemical and anthropometric parameters in patients with MetS.


This randomized controlled clinical trial was conducted on 37 patients with MetS. We supplemented the individuals with MetS with either 2 g per day ginger powder or placebo for 12 weeks. Biochemical and anthropometric parameters before and after the intervention were compared between the two groups.


After 12 weeks of treatment, the levels of triglyceride (TG), FBS, and insulin resistance were significantly improved in the patients receiving ginger in compare to the placebo group (P < 0·05). Moreover, significant changes were observed in terms of weight, waist circumference, LDL, HDL, total cholesterol, systolic and diastolic blood pressure and energy intake between the groups.


In general, our findings demonstrated that the ginger supplementation offers beneficial effects on patients with MetS, at least, in part due to the modulatory effects on TG, FBS, and insulin resistance.


Ginger Metabolic syndrome Insulin resistance Lipid profile 



This study was supported by a grant from the Tehran Medical University. We hereby appreciate the participation of the patients as well as the cooperation of the staff at the National Nutrition and Food Technology Research Institute of the Shahid Beheshti University. We also appreciate Mr. Mousa Vatanmakanian for the critical revision and language editing of the manuscript.

Compliance with ethical standards

Conflict of interest

The authors disclose no conflicts of interest.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Mehran Rahimlou
    • 1
    • 2
  • Zahra Yari
    • 3
  • Elham Rayyani
    • 1
  • Seyed Ali Keshavarz
    • 1
  • Seyedahmad Hosseini
    • 2
  • Nava Morshedzadeh
    • 3
  • Azita Hekmatdoost
    • 3
    Email author
  1. 1.Department of Clinical Nutrition, School of Nutritional Sciences and DieteticsTehran University of Medical Sciences (TUMS)TehranIran
  2. 2.School of ParamedicineAhvaz Jundishapur University of Medical SciencesAhvazIran
  3. 3.Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research InstituteShahid Beheshti University of Medical ScienceTehranIran

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