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Current Anesthesiology Reports

, Volume 9, Issue 2, pp 194–201 | Cite as

Transfusion Requirements in Anesthesia and Intensive Care

  • Daniel BolligerEmail author
  • Andreas Buser
  • Kenichi A. Tanaka
Critical Care Anesthesia (BS Rasmussen, Section Editor)
  • 53 Downloads
Part of the following topical collections:
  1. Critical Care Anesthesia

Abstract

Purpose of Review

Allogeneic blood products are commonly used in perioperative and critically ill patients. This review focuses on the current evidence and emerging data relating to modern transfusion strategies in these patients.

Recent Findings

Several large randomized trials and meta-analyses found no inferiority of a restrictive strategy as compared to a liberal one in red blood cell (RBC) transfusion. The storage duration of transfused RBC seems to have a minor, if any, impact on patients’ outcome. However, patients requiring massive transfusions might be an exception. The indications and benefits of plasma and platelets transfusions are less clear because robust clinical evidence is missing.

Summary

In contrast to the established evidence and practice for RBC transfusion, the limited evidence for plasma and platelets transfusions call for incorporating expert opinions and guidelines and for standardized local practice. Targeted hemostatic interventions are preferred over prophylactic fixed-ratio transfusions in terms of efficacy and avoidance of transfusion-related complications.

Keywords

Transfusion Red blood cells Platelets Fresh frozen plasma Blood components 

Notes

Compliance with Ethical Standards

Conflict of Interest

Daniel Bolliger, Andreas Buser, and Kenichi A. Tanaka declare they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Daniel Bolliger
    • 1
    Email author
  • Andreas Buser
    • 2
  • Kenichi A. Tanaka
    • 3
  1. 1.Department for Anesthesia, Surgical Intensive Care, Prehospital Emergency Medicine, and Pain TherapyUniversity Hospital BaselBaselSwitzerland
  2. 2.Regional Blood Transfusion Service, Swiss Red Cross, Basel, and Department of HematologyUniversity Hospital BaselBaselSwitzerland
  3. 3.Department of Anesthesiology, Cardiothoracic Anesthesia DivisionUniversity of MarylandBaltimoreUSA

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