Current Anesthesiology Reports

, Volume 8, Issue 4, pp 362–367 | Cite as

New Cancer Therapies: Implications for the Perioperative Period

  • Tayab AndrabiEmail author
  • Katy E. French
  • Muzaffar H. Qazilbash
Cancer Anesthesia (B Riedel and V Gottumukkala, Section Editors)
Part of the following topical collections:
  1. Cancer Anesthesia


Purpose of Review

Cancer is on the rise. Standing on verge of exciting discoveries, research is being translated into therapies that are being widely administered to patients. Providing a hope for cure, where none existed before. This new body of knowledge has come from a better understanding of cancer genetics, molecular and sub molecular behavior, and understanding of cancer-generated cellular environments. These have led to development of immunotherapy and its many sub-genres, improvement and introduction of new radiation technologies, and decreasing toxicities of existing chemotherapies.

Recent Findings

The purpose of this review is to have a summary look at this huge landscape of cancer therapy. Specially looking at toxicities that an anesthesiologist should be familiar with while providing perioperative care for these patients, complications like tumor lysis syndrome, cytokine release syndromes, Kounis syndrome, myocarditis, encephalopathies, and pituitary failure need to be kept in mind.


One should be knowledgeable about these therapies and approach these patients with a high index of suspicion. Anesthesiologists will need to refine preoperative assessment with appropriate testing and intraoperative and postoperative management in collaboration with oncologists, while involving the expertise of internists, cardiologist, and endocrinologists in helping assess and manage these patients in the perioperative period.


Anesthesia assessment in cancer patients Perioperative implications of cancer therapy New cancer therapies, side effects, and management in perioperative period Immunotherapy, mechanism of actions, and side effects Side effects 


Compliance with Ethical Standards

Conflict of Interest

TayabAndrabi, Katy E. French, and Muzaffar H. Qazilbash declare they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Tayab Andrabi
    • 1
    Email author
  • Katy E. French
    • 2
  • Muzaffar H. Qazilbash
    • 3
  1. 1.Anesthesiology and PeriOper Med, Margaret and Ben Love Clinic (R6.1365)The University of Texas MD Anderson Cancer CenterHoustonUSA
  2. 2.Anesthesiology and PeriOper Med, Margaret and Ben Love Clinic (R6.1370)The University of Texas MD Anderson Cancer CenterHoustonUSA
  3. 3.Stem Cell Transplantation, John Mendelsohn Faculty Center (FC5.2006)The University of Texas MD Anderson Cancer CenterHoustonUSA

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