Green synthesis of Terminalia arjuna-conjugated palladium nanoparticles (TA-PdNPs) and its catalytic applications
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Synthesis of metal nanoparticles from the metal salts by reduction with plant extracts in water, without any additional stabilizing or capping agents is a green and eco-friendly method. In the present work, aqueous extract of the bark of Terminalia arjuna was utilized to synthesize T. arjuna-conjugated palladium nanoparticles (TA-PdNPs) from palladium chloride. The dark brown colour indicating the formation of TA-PdNPs appeared within 3 h without heating but, on heating colour appeared almost instantly. The synthesized TA-PdNPs are characterized by UV spectroscopy, HRTEM and XRD studies. The TA-PdNPs were utilized as efficient catalyst for Heck and Suzuki type C–C coupling reactions and degradation of organic dyes in aqueous medium at room temperature.
KeywordsPalladium nanoparticle Terminalia arjuna Green synthesis Catalyst C–C coupling Dye degradation
Metal nanoparticles have drawn a great attention of scientific community due to a combination of their shape and size dependent unique properties like chemical, physical, theromodynamic, optical, electronic etc. and these have found increasing applications in pharmacology, bio-diagnostics, medicine, drug-delivery, catalysis, coatings, solar cells, purification of water, etc. [1, 2, 3, 4, 5, 6, 7, 8, 9]. Palladium nanoparticles are highly interesting than other transition metal nanoparticles for their usefulness in both homogeneous as well as heterogeneous catalysis due to their high surface-to-volume ratio and high surface energy. Use of palladium nanoparticles as a catalyst for various C–C coupling reactions such Suzuki and Heck coupling reactions has been highly exploited in organic synthesis [10, 11, 12, 13, 14, 15]. Palladium nanoparticles have also been used as a catalyst in hydrogenation of alkenes, alkynes, allyl and benzyl alcohols and hydrogenolysis of allylic and benzylic ethers [16, 17, 18]. However, the examples of the utilization of phytochemical-conjugated PdNPs in C–C coupling reactions and degradation of dyes are rare [19, 20, 21].
Water pollution has been a great concern in modern civilization due to contamination of natural water mainly by human activities. For example, use of different colouring textile dyes which are toxic in nature pollute water through drainage . So detoxification or transformation of these dyes into a non dangerous substance is a challenge. Palladium nanoparticles can be utilized for the reductive degradation of dyes . Several methods have been developed and modified to synthesize metal nanoparticles. But, use of toxic chemicals in those methods, limits their application. Use of non-toxic bio molecules to synthesize Pd nanoparticles without using hazardous chemicals under mild reaction conditions is a greener and environment-friendly method [24, 25, 26, 27, 28, 29]. Among the various methods reported for the synthesis of the palladium nanoparticles, a bottom-up synthetic strategy by the plant extract-mediated reductive method, involving reduction of Pd(II) to Pd(0) by phytochemicals, has gained profound significance in recent years due to the renewable and non-toxic nature of the phytochemicals, mild reaction condition, eco-friendly aqueous medium etc. The advantage of this method is that, additional stabilizers are not required to synthesize PdNPs which is important to sustain active surface of PdNPs and prevent generation of less active black palladium  and here the plant extract itself acts as a stabilizer. The leaf extracts of Chrysophyllum cainito , xanthan gum , Glycine max leaf , Cinnamomum camphora leaf , Hippophae rhamnoides Linn leaf  have been utilized for synthesis of PdNPS. Terminalia arjuna is a well known medicinal plant and its stem bark is rich in various plant secondary metabolites such as terpenoids, flavonoids including polyphenols, steroids and glycosides [35, 36, 37, 38, 39, 40, 41, 42, 43]. Herein, we report the synthesis PdNPs using the bark extract of T. arjuna. The polyphenols acted as reducing and stabilizing agents for the synthesis of T. arjuna-conjugated PdNPs (TA-PdNPs). Characterization of TA-PdNPs was carried out by Surface Plasmon resonance (SPR) spectroscopy, High-resolution transmission electron microscopy (HRTEM) and X-Ray diffraction studies. The synthesized TA-PdNPs were utilized as an excellent catalyst for C–C coupling reactions (Suzuki and Heck coupling without phosphine) and reductive degradation of dyes (methylene blue and rhodamine-B) in aqueous medium.
Materials and instruments
Details of materials used and instruments required to characterize TA-PdNPs are discussed in supporting information.
Preparation of Terminalia arjuna bark extract
Dried T. arjuna bark (30 g) was powdered and boiled with 200 mL of distilled water for 15 min and then filtered through Whatman 1 filter paper. The concentration of the extract was 6000 mg L−1, as determined by evaporation of 1 mL of the extract that contained 6 mg of the dried extract.
Synthesis of palladium nanoparticles
Palladium nanoparticles (TA-PdNPs) were synthesized by heating the mixture of palladium chloride solution (0.4 mL, 5.019 mM) and the bark extract of T. arjuna at 60–70 °C for 2 min. Then the reaction mixture was kept at room temperature for 1 h. We have prepared a series of TA-PdNPs containing different concentration of the bark extract of T. arjuna ranging from 200 to 1600 mg L−1. Palladium chloride solution (0.4 mL, 5.019 mM each) was added to each vial and the final volume was made up to 2 mL thereby keeping the concentration PdNPs fixed (1.004 mM).
C–C coupling reactions
Suzuki and Heck coupling reactions were carried out by following a procedure reported by us previously .
Catalytic efficiency of stabilized TA-PdNPs towards reductive degradation of dyes was investigated by reduction of two chemical dyes methylene blue (MB) and rhodamine-B (Rh-B) with sodium borohydride (16.5 mM). The reduction reaction was monitored by UV spectroscopy.
Results and discussion
Characterization of TA-PdNPs
Mechanism of the formation of TA-PdNPs
C–C coupling reactions
Suzuki ReactionSuzuki reaction was carried out using iodobenzene (0.5 mmol), phenylboronic acid (0.77 mmol) and K2CO3 (1 mmol) as a base in the presence of TA-PdNPs (0.079 mol % with respect to iodobenzene) as catalyst in water at 100 °C (Fig. 5a). The reaction was complete after 9 h and the isolated yield of purified product was 99.3%. The catalytic turn over number (TON) and the turn over frequency (TOF) for Suzuki reaction were calculated to be 1241 and 138 h−1, respectively.
Heck reaction was performed using iodobenzene (1 mmol), methyl acrylate (1.5 mmol), Et3N as base and TA-PdNPs (0.11 mol % with respect to iodobenzene) as catalyst in 1:1 DMF–water mixture at 90 °C (Fig. 5b). The reaction was complete in 5 h and the yield of the purified product was 95.5%. The catalytic turn over number (TON) and the turn over frequency (TOF) for Heck reaction were calculated to be 996 and 190 h−1, respectively.
Reduction of methylene blue dyeOn treatment of an aqueous solution of methylene blue (0.5 mM) with sodium borohydride (16.5 mM), the position of the absorption band at 663 nm did not change and only a minute decrease in intensity of this band was observed with time (Fig S5a). This was due to very slow rate of reduction the dye because of for large kinetic energy barrier for the reduction reaction. But after addition of colloidal TA-PdNPs (0.1 mL) synthesized from bark extract of T. arjuna (800 mg L−1) to reaction mixture, the colour of dye as well as absorption band at 663 nm disappeared within fraction of second due to the formation of leuco methylene blue . For the calculation of rate constant we tried to slow down the rate of reaction by diluting the colloidal TA-PdNPs by ten times (100 μL of colloidal TA-PdNPs diluted to 1 mL in distilled water) and on addition of this diluted TA-PdNPs (0.1 mL) to reaction mixture, the colour of dye also disappeared within a few seconds. Then again the colloidal TA-PdNPs was diluted to 100 times and the reaction completed in 9 min (Fig. 6) on addition of 0.075 mL diluted TA-PdNPs to reaction mixture. Similarly, on addition of 0.05 mL of 100 times diluted TA-PdNPs to reaction mixture the absorption band at 663 nm decreases slowly and completely disappear in 15 min (Fig. S6). For these reduction reactions the calculated rate constants were 0.141 min−1 and 0.139 min−1 (Fig. S8c and S8d), respectively, which are consistent with previous reports . The catalytic turn over number (TON) and the turn over frequency (TOF) for the degradation of methylene blue were calculated to be 133 and 14.8 min−1, respectively.
Reduction of Rhodamine-B dyeOn treatment of an aqueous solution of rhodamine-B (0.5 mM) with sodium borohydride (16.5 mM) at room temperature, the absorption band at 553 nm did not change its position. A very slow decrease in intensity of the absorption band was observed with time due to slow reduction of rhodamine-B with sodium borohydride (Fig S5b). But when colloidal TA-PdNPs (0.1 mL) synthesized from bark extract of T. arjuna (800 mg L−1) was added to reaction mixture the absorption band at 553 nm as well as the pink colour disappeared in fraction of a second due to the formation of colourless leuco rhodamine-B . Hence, for calculating rate constant we tried to slow down the rate of the reaction by diluting the stabilized TA-PdNPs. By addition of 0.1 mL of both 10 times as well as 100-times diluted TA-PdNPs to reaction mixture the colour of reaction mixture disappeared within few seconds and rate could not be calculated. So the stabilized TA-PdNPs were further diluted. After 500 times dilution of TA-PdNPs, the reaction was completed in 9 min by addition of 0.1 mL of diluted TA-PdNPs (Fig. 7). Similarly, on addition of 0.05 mL of 500-times diluted TA-PdNPs to reaction mixture the absorption band at 553 nm decreases slowly and completely disappear in 54 min (Fig. S7). For these reduction reactions the calculated rate constants were 0.52 min−1 and 0.062 min−1 (Fig. S8a and S8b), respectively, which are also consistent with previous reports . The catalytic turn over number (TON) and the turn over frequency (TOF) for the degradation of rhodamine-B were calculated to be 500 and 55 min−1, respectively.
Terminalia arjuna-conjugated PdNPs (TA-PdNPs) were synthesized using the non-toxic bark extract of T. arjuna and PdCl2 solution having average diameter of PdNPs of 8.9 nm. The small-sized aqueous colloidal TA-PdNPs were utilized as an efficient catalyst for the Suzuki and Heck type C–C coupling reaction under phosphine-free conditions in excellent yields making it useful in synthetic organic chemistry. Excellent catalytic activity of TA-PdNPs towards reductive degradation of dyes such as methylene blue and rhodamine-B in the presence of sodium borohydride has also been demonstrated in aqueous medium making it useful for the removal of toxic industrial pollutants.
CG thanks UGC for providing Faculty Development Programme (FDP). SNH, ACB and SKP thank UGC, New Delhi and SG thanks CSIR, New Delhi for research fellowships. BGB thanks India-Srilanka project (DST/INT/SL/P25/2016), SERB, India (EMR/2016/001123), UGC-MRPMAJOR-CHEM-2013-35629, UGC-SAP DRS II and DST-FIST New Delhi and Vidyasagar University for financial support and infrastructural facilities.
This study was funded by a Grant of the SERB, India (EMR/2016/001123), India–Srilanka project (DST/INT/SL/P25/2016), New Delhi.
Compliance with ethical standards
Conflict of interest
The authors declare no conflict of interest.
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