Efficacy of electrochemically activated water solution in gingivitis treatment
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Mouthwash is one of the most commonly oral healthcare products for prevention and treatment of gum diseases. Dr. ECA is a disinfectant solution manufactured by a Vietnamese company and has been licensed for oral healthcare, but its effect on gingivitis is still unclear. To evaluate the effectiveness of this product in the treatment of gingivitis, we conducted a clinical study in 60 students diagnosed with gingivitis to compare the results of gingivitis treatment using Dr. ECA and a control mouthwash (a demonstrated anti-gingivitis product). The data showed that in the treated group, the rate of good Gingivitis Index (GI) before treatment was 46.67%, but after 2 and 4 weeks of using Dr. ECA that rate was increased to 96.67% and 100%, respectively. The percentage of patients with bleeding on probing was 63.33% but declined sharply after 2 weeks of treatment to 6.67%, and further reduced to 3.33% after 4 weeks of treatment. The treatment outcomes in were similar in the Dr. ECA treated group and control one with no statistically significant difference. Our results suggest that the electrolyte saline solution Dr. ECA is effective in treating gingivitis. Its effects are similar to other mouthwash products that had been approved and marketed.
KeywordsMouthwash Electrochemically activated water solutions Dr. ECA Gingivitis
TNNV and DTC designed experiments. VTNV, DLD, VNB and MST, TTPN and QAL designed, performed experiments, and collected data and informed consents. TNNV, DTC, KHN, VHP, and TCD analyzed and interpreted the results. VTNV, DLD, DTC, VHP, and TCD wrote the manuscript. DTC, KHN, VHP, and TCD edited the manuscript. All authors approved the final manuscript.
The EVD Group provided Dr. ECA solution and a part of the expenses for this research.
Compliance with ethical standards
Conflict of interest
The authors declare no conflict of interest.
All procedures performed in this study involving human participants were in accordance with the ethical standards of the Hanoi Medical University’s Ethics Council committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study was approved by the Hanoi Medical University’s Ethics Council committee (No. 121/HMU IRB).
Informed consent was obtained from the patients included in the study.
- Ignatov I, Gluhchev G, Karadzhov S, Miloshev G, Ivanov N, Mosin O (2015a) Preparation of electrochemically activated water solutions (catholyte/anolyte) and studying their physical-chemical properties. J Health Med Nurs 13:64–78Google Scholar
- Ignatov I, Gluhchev G, Karadzhov S, Miloshev G, Ivanov N, Mosin O (2015b) Preparation of electrochemically activated water solutions (catholyte/anolyte) and studying their physical-chemical properties. J Med Physiol Biophys 11:1–21Google Scholar
- Maria Augusta Bessa Rebelo ACdQ (2011) Gingival indices: state of art, gingival diseases - their aetiology, prevention and treatment InTech Europe, Croatia, pp 4–53Google Scholar
- Ngân NHK, Nghĩa LL, Hương ĐTL (2015) Đặc điểm lâm sàng viêm lợi và hiệu quả điều trị viêm lợi mảng bám đơn thuần có sử dụng nước súc miệng Chlohexidine ở sinh viên Trường ĐH Y Hà Nội. BSYK—Trường đại học y Hà NộiGoogle Scholar
- Ngoc VTN et al (2018) The higher prevalence of developmental defects of enamel in the dioxin-affected region than non-dioxin-affected region: result from a cross-sectional study in Vietnam. OdontologyGoogle Scholar
- Prilutsky VIВ, Bakhir VM (1997) Electrochemically activated water: Anomalous properties, Mechanism of biological action. Moscow: VNIIIMT:1, p 124Google Scholar