Neue Arzneikombination bessert Schweißtest und Lungenfunktion
Cystische Fibrose
journal club
First Online:
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Literatur
- 1.Van Goor F, Hadida S, Grootenhuis PD et al. Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809. Proc Natl Acad Sci USA 2011; 108: 18843–48.PubMedCrossRefPubMedCentralGoogle Scholar
Literatur
- Boyle M, Bell SC, Konstan MW et al. A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial. Lancet Respir Med. 2014 Jul;2(7):527–38.PubMedCrossRefGoogle Scholar
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© Urban & Vogel 2014