Infection

, Volume 27, Issue 6, pp 365–367

Rapid Diagnosis of Primary Dengue Fever by the Immunochromatographic Test and by Electron Microscopy – A Case Report

  • Regina Allwinn
  • C. Schieferstein
  • S. Glauke
  • H.W. Doerr
Case Reports

Summary

A 21-year-old women presented with an acute febrile illness after a two-week holiday in Jamaica. Her symptoms started two days after return, with sudden onset of continuous higher fever (> 39 °C), dizziness and nausea. Three days later she developed a generalized macular rash, which led to the tentative diagnosis “acute dengue fever”. Laboratory confirmation was achieved by demonstrating anti-dengue IgM and IgG antibodies in paired sera; in addition, flavivirus particles were directly visualized by electron microscopy.

Key words Dengue Rapid diagnosis Serology Flavivirus 

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Copyright information

© Urban & Vogel Medien und Medizin Verlagsgesellschaft 1999

Authors and Affiliations

  • Regina Allwinn
    • 1
  • C. Schieferstein
    • 1
  • S. Glauke
    • 1
  • H.W. Doerr
    • 1
  1. 1.Institute for Medical Virology, J.W.Goethe University Frankfurt/Main, Sandhofstr. 2–4, D-60528 Frankfurt a. M., Germany, e-mail: Allwinn@em.uni-frankfurt.deDE

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