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Infection

pp 1–4 | Cite as

Vertebral osteomyelitis due to Candida species

  • Nathan McLeodEmail author
  • Melanie Fisher
  • P. Rocco Lasala
Brief Report

Abstract

Objective

We have noted an increased number of cases of vertebral osteomyelitis secondary to Candida species over the past few years at our facility. Our aim was to identify and review these cases to elucidate risk factors, treatment regimens and outcomes.

Methods

We performed a retrospective chart review using our electronic medical record and microbiology laboratory database to identify cases of vertebral osteomyelitis due to Candida at a single teaching hospital from 2006–2018.

Results

We found 15 cases of Candida vertebral osteomyelitis. The majority of cases were due to Candida albicans and affected either the lumbar or the thoracic spine. Injection drug use and previous spine surgery were the two most common risk factors identified. Treatment was largely with intravenous antifungal induction followed by prolonged therapy with oral fluconazole. There was no short-term mortality though we lacked long-term follow-up on most patients.

Conclusions

The number of vertebral infections due to Candida may be increasing. This may be partially driven by both a rise in intravenous drug use as well as the growing rate of spine surgery. Management following currently available guidelines seems favorable, though further studies are necessary to determine the optimal treatment regimen.

Keywords

Candida Vertebral osteomyelitis Diskitis Injection drug use Candida infections 

Notes

Funding

None.

Compliance with ethical standards

Conflict of interest

The authors have no competing interest.

Ethical approval

West Virginia University Institutional Review Board approved this study.

Informed consent

No informed consent was required due to the retrospective nature of this study and no patient identifying information was utilized in this publication.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Medicine, Section of Infectious DiseasesWest Virginia University School of MedicineMorgantownUSA
  2. 2.Department of Pathology and Laboratory MedicineWest Virginia University School of MedicineMorgantownUSA

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