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Infection

pp 1–9 | Cite as

Correlation between Streptococcus bovis bacteremia and density of cows in Galicia, northwest of Spain

  • J. Corredoira
  • E. Miguez
  • L. M. Mateo
  • R. Fernández-Rodriguez
  • J. F. García-Rodriguez
  • A. Peréz-Gonzalez
  • A. Sanjurjo
  • M. V. Pulian
  • R. Rabuñal
  • GESBOGA
Original Paper

Abstract

Background

There are few data on the epidemiology of infections caused by Streptococcus bovis (Sb). Some studies suggest that both residence in rural areas and contact with livestock could be potential risk factors.

Methods

We performed a retrospective study for the period 2005–2016 of all cases of bacteremia caused by Sb in Galicia (a region in the northwest of Spain). The association between the incidence rate of Sb bacteremia and the number of cattle by province and district was analyzed.

Results

677 cases were included with a median age of 76 years, 69.3% males. The most frequent infections were endocarditis (234 cases, 34.5%), primary bacteremia (213 cases, 31.5%) and biliary infection (119 cases, 17.5%). In 252 patients, colon neoplasms were detected (37.2%). S. gallolyticus subsp. gallolyticus was the predominant species (52.3%). Mortality was 15.5% (105 cases). The annual incidence rate was 20.2 cases/106 inhabitants and was correlated with the density of cattle (p < 0.001), but not with rurality. When comparing the two provinces with a strong predominance of rural population, but with important differences in the number of cattle, such as Orense and Lugo, with 6% and 47.7% of Galician cattle, respectively, the rates were very different: 15.8 and 43.6 cases/106, respectively, with an RR of 2.7 (95% CI, 2.08–3.71). Some districts of the province of Lugo had rates higher than 100 cases/106 inhabitants.

Conclusions

Our study shows a significant correlation between the rates of Sb bacteremia and cattle density, suggesting a possible transmission of Sb from cows to people.

Keywords

Streptococcus bovis Bacteremia Cattle 

Notes

Acknowledgements

List of Collaborators:

GESBOGA—Study Group of Streptococcus bovis bacteremia in Galicia: List of participating centers and researches: Hospital da Costa (Burela, Lugo): Serrano M (Microbiology), Jove MJ (Internal Medicine); Hospital Comarcal de Monforte de Lemos (Lugo): Alonso P (Microbiology), Justo E, Piñeiro JC (Internal Medicine); Hospital Universitario Lucus Augusti (Lugo): Alonso MP, García-Garrote F, Coira MA (Microbiology), Blanco A (Methodology and Clinical Research Unit. Ramón Domínguez Foundation), Gómez-Méndez R (Internal Medicine), García-Pais MJ, Rabuñal R, López-Álvarez MJ, J Corredoira, Eva Romay (Infectious Diseases Unit); Hospital Virxe da Xunqueira (Cee, A Coruña): Abel V (Internal Medicine); Complexo Hospitalario Universitario A Coruña (A Coruña): Miguez E (Infectious Diseases Unit), Cerezales A, Vieito D (Internal Medicine), Rodriguez-Mayo M, Gude MJ (Microbiology); Complexo Hospitalario Universitario de Ferrol (Ferrol, A Coruña): García-Rodríguez JF (Infectious Diseases Unit), Agulla JA (Microbiology); Complexo Hospitalario Universitario de Santiago (Santiago de Compostela, A Coruña): Mateo LM, González-Quintela A (Internal Medicine), Hernández M, Manso T, Aguilera A, Pérez del Molino ML (Microbiology), Hospital da Barbanza (Ribeira, A Coruña): Martínez-Braña L (Internal Medicine); Complexo Hospitalario Universitario de Ourense (Ourense): Fernández-Rodríguez R (Infectious Diseases Unit), Paz MI (Microbiology); Hospital de Valdeorras (O Barco de Valdeorras, Ourense), González-Dominguez M (Microbiology), Morales F (Internal Medicine); Hospital de Verín (Verín, Ourense): Soto I (Internal Medicine); Complexo Hospitalario Universitario de Vigo (Vigo, Pontevedra): Vasallo FJ (Microbiology), Pérez-Gonzalez A, Pérez-Alvarez R (Internal Medicine); Hospital POVISA (Vigo, Pontevedra): de la Fuente J, Sanjurjo A, Lamas JL, Álvarez-Ferreiro J (Internal Medicine), Rodríguez-Conde MI (Microbiology), Hospital do Salnes (Vilagarcia de Arousa, Pontevedra), Pazos A (Internal Medicine); Complexo Hospitalario Universitario de Pontevedra (Pontevedra), Pulian MV, Guzmán DM, García-Campello M (Microbiology), Diz J (Internal Medicine).

Funding

No grant support was available for this investigation.

Compliance with ethical standards

Ethical statement

The Institutional Review Boards approved this study, and they specifically waived the need for consent because the study analyzed the data retrospectively and the source of data was anonymized.

Conflict of interest

All authors declare no conflicts of interest with this investigation.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • J. Corredoira
    • 1
  • E. Miguez
    • 2
  • L. M. Mateo
    • 3
  • R. Fernández-Rodriguez
    • 4
  • J. F. García-Rodriguez
    • 5
  • A. Peréz-Gonzalez
    • 6
  • A. Sanjurjo
    • 7
  • M. V. Pulian
    • 8
  • R. Rabuñal
    • 1
  • GESBOGA
  1. 1.Infectious Diseases UnitHospital Universitario Lucus AugustiLugoSpain
  2. 2.Infectious Diseases UnitComplexo Hospitalario Universitario A CoruñaA CoruñaSpain
  3. 3.Internal MedicineComplexo Hospitalario Universitario de SantiagoSantiago de CompostelaSpain
  4. 4.Infectious Diseases UnitComplexo Hospitalario Universitario de OurenseOurenseSpain
  5. 5.Infectious Diseases UnitComplexo Hospitalario Universitario de FerrolFerrolSpain
  6. 6.Internal MedicineComplexo Hospitalario Universitario de VigoVigoSpain
  7. 7.Internal MedicineHospital POVISAVigoSpain
  8. 8.MicrobiologyComplexo Hospitalario Universitario de PontevedraPontevedraSpain

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