Fecal microbiota transplantation in a kidney transplant recipient with recurrent urinary tract infection
We report on a kidney transplant recipient treated with fecal microbiota transplantation (FMT) for recurrent urinary tract infections.
FMT was administered via frozen capsulized microbiota. Before and after FMT, urinary, fecal and vaginal microbiota compositions were analyzed.
The patient remained without symptoms after FMT.
Underlying mechanisms of action need to be addressed in depth by future research.
KeywordsRecurrent urinary tract infection Fecal microbiota transplantation Urinary microbiome Non-antibiotic prophylaxis
We thank the patient for provision of clinical data and Anastasia Tsakmaklis and Fabiola Sack for excellent laboratory support.
This work was supported by the German Research Foundation (DFG) [BI 1899/1-1].
Compliance with ethical standards
Conflict of interest
LMB has received lecture honoraria from Astellas and Merck/MSD, and travel grants from 3M and Gilead. MJGTV reports grants and personal fees from Astellas Pharma, Merck/MSD, Gilead Sciences, Berlin Chemie, Falk Foundation, Organobalance, Pfizer, and grants from Astellas Pharma, Merck/MSD, Seres Therapeutics, DaVolterra. All other authors: none to declare.
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