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Infection

pp 1–4 | Cite as

Fecal microbiota transplantation in a kidney transplant recipient with recurrent urinary tract infection

  • Lena M. Biehl
  • Rebeca Cruz Aguilar
  • Fedja Farowski
  • Werner Hahn
  • Angela Nowag
  • Hilmar Wisplinghoff
  • Maria J. G. T. Vehreschild
Case Report

Abstract

Purpose

We report on a kidney transplant recipient treated with fecal microbiota transplantation (FMT) for recurrent urinary tract infections.

Methods

FMT was administered via frozen capsulized microbiota. Before and after FMT, urinary, fecal and vaginal microbiota compositions were analyzed.

Results

The patient remained without symptoms after FMT.

Conclusions

Underlying mechanisms of action need to be addressed in depth by future research.

Keywords

Recurrent urinary tract infection Fecal microbiota transplantation Urinary microbiome Non-antibiotic prophylaxis 

Notes

Acknowledgements

We thank the patient for provision of clinical data and Anastasia Tsakmaklis and Fabiola Sack for excellent laboratory support.

Funding

This work was supported by the German Research Foundation (DFG) [BI 1899/1-1].

Compliance with ethical standards

Conflict of interest

LMB has received lecture honoraria from Astellas and Merck/MSD, and travel grants from 3M and Gilead. MJGTV reports grants and personal fees from Astellas Pharma, Merck/MSD, Gilead Sciences, Berlin Chemie, Falk Foundation, Organobalance, Pfizer, and grants from Astellas Pharma, Merck/MSD, Seres Therapeutics, DaVolterra. All other authors: none to declare.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department I of Internal MedicineUniversity Hospital of CologneCologneGermany
  2. 2.German Centre for Infection Research, Partner Site Bonn-CologneCologneGermany
  3. 3.Practice for Nephrology and Hypertension, DialysisMayenGermany
  4. 4.Wisplinghoff LaboratoriesCologneGermany
  5. 5.Institute for Medical Microbiology, Immunology and HygieneUniversity of CologneCologneGermany
  6. 6.Institute for Virology and Medical MicrobiologyWitten/Herdecke UniversityWittenGermany

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