, Volume 46, Issue 6, pp 847–853 | Cite as

Epidemiology, clinical and laboratory features of 24 consecutive cases of leptospirosis at a German infectious disease center

  • Thomas Theo BrehmEmail author
  • Julian Schulze zur Wiesch
  • Marc Lütgehetmann
  • Dennis Tappe
  • Philip Eisermann
  • Ansgar W. Lohse
  • Marylyn M. Addo
  • Stefan Schmiedel
Brief Report


To determine epidemiological, clinical and laboratory characteristics of leptospirosis, 24 consecutive patients diagnosed with the infection between 2011 and 2017 at the University Medical Center Hamburg-Eppendorf were retrospectively analyzed. The majority of patients were male travelers who returned from Southeast Asia and had a history of freshwater-associated activities. Considering the lack of discriminatory clinical or clinical chemistry parameters, leptospirosis should be regarded as differential diagnosis in any patient with acute febrile illness, especially with a history of travel to tropical and subtropical regions or freshwater exposure.


Leptospirosis Zoonosis Traveler Germany Southeast Asia 


Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Ethical standards

Only parameters collected in routine clinical practice for which patients give their informed consent on admission to the hospital were retrospectively analyzed. An approval by an ethics committee was not applicable.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Thomas Theo Brehm
    • 1
    • 4
    Email author
  • Julian Schulze zur Wiesch
    • 1
    • 4
  • Marc Lütgehetmann
    • 2
    • 4
  • Dennis Tappe
    • 3
    • 4
  • Philip Eisermann
    • 3
    • 4
  • Ansgar W. Lohse
    • 1
    • 4
  • Marylyn M. Addo
    • 1
    • 4
  • Stefan Schmiedel
    • 1
    • 4
  1. 1.I. Department of MedicineUniversity Medical Center Hamburg-EppendorfHamburgGermany
  2. 2.Institute of Microbiology, Virology and HygieneUniversity Medical Center Hamburg-EppendorfHamburgGermany
  3. 3.Bernhard Nocht Institute for Tropical MedicineHamburgGermany
  4. 4.German Centre for Infection Research (DZIF)Partner Site Hamburg-Lübeck-Borstel-RiemsGermany

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