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Infection

, Volume 46, Issue 5, pp 693–699 | Cite as

Epidemiology, management and outcome of varicella in pregnancy: a 20-year experience at the Tuscany Reference Centre for Infectious Diseases in Pregnancy

  • Michele Trotta
  • Beatrice Borchi
  • Alessandra Niccolai
  • Elisabetta Venturini
  • Susanna Giaché
  • Gaetana Sterrantino
  • Maria Grazia Colao
  • Gian Maria Rossolini
  • Alessandro Bartoloni
  • Lorenzo Zammarchi
Brief Report
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Abstract

Data from 215 pregnant women exposed to varicella and 276 with varicella observed at the Tuscany Reference Center for Infectious Diseases in Pregnancy, Florence, Italy, in the period 1997–2016 were retrospectively collected. The risk of developing varicella was lower in exposed women who received varicella zoster immunoglobulin compared with those who did not receive it [42% (21 of 50) vs 72% (13 of 18); p = 0.0263]. Typical congenital varicella syndrome was observed in 1.56% of fetuses/neonates born from pregnant women with varicella.

Keywords

Varicella Immunoglobulin Congenital Chickenpox Varicella zoster virus VZIG 

Notes

Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Michele Trotta
    • 1
    • 2
  • Beatrice Borchi
    • 1
    • 2
  • Alessandra Niccolai
    • 3
  • Elisabetta Venturini
    • 4
    • 5
  • Susanna Giaché
    • 6
  • Gaetana Sterrantino
    • 1
  • Maria Grazia Colao
    • 7
  • Gian Maria Rossolini
    • 6
    • 7
  • Alessandro Bartoloni
    • 1
    • 6
  • Lorenzo Zammarchi
    • 1
    • 2
    • 6
  1. 1.SOD Malattie Infettive e TropicaliAzienda Ospedaliero-Universitaria CareggiFlorenceItaly
  2. 2.Centro di Riferimento per la Regione Toscana per le Malattie Infettive in GravidanzaAzienda Ospedaliero-Universitaria CareggiFlorenceItaly
  3. 3.Scuola di Scienze della Salute Umana, Corso di Laurea in OstetriciaUniversità degli Studi di FirenzeFlorenceItaly
  4. 4.Unità di Malattie InfettiveAzienda Ospedaliero Universitaria MeyerFlorenceItaly
  5. 5.Dipartimento di Scienze della SaluteUniversità degli Studi di FirenzeFlorenceItaly
  6. 6.Dipartimento di Medicina Sperimentale e ClinicaUniversità degli Studi di FirenzeFlorenceItaly
  7. 7.SOD Microbiologia e VirologiaAzienda Ospedaliero-Universitaria CareggiFlorenceItaly

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