Possible pulmonary Rhizopus oryzae infection in a previously healthy child after a near-drowning incident
Case Report
First Online:
Received:
Accepted:
- 186 Downloads
Abstract
This article reports on a previously healthy 17-month-old boy who developed pulmonary mucormycosis after a near-drowning incident in a goose pond. The patient survived without neurological sequelae and recovered, under treatment with amphotericin B, from the rare and often invasive fungal infection with Rhizopus spp., usually occurring in immunodeficient patients.
Keywords
Pulmonary mucormycosis Rhizopus spp. Near-drowning Cooling procedureNotes
Acknowledgments
This work was supported by Studienstiftung des Deutschen Volkes (to M. M. G.).
Compliance with ethical standards
Conflict of interest
On behalf of all authors, the corresponding author states that there is no conflict of interest.
References
- 1.Brüning C, Siekmeyer W, Siekmeyer M, Merkenschlager A, Kiess W. Retrospective analysis of 44 childhood drowning accidents. Wien Klin Wochenschr. 2010;122:405–12.CrossRefPubMedGoogle Scholar
- 2.van Dam AP, Pruijm MT, Harinck BI, Gelinck LB, Kuijper EJ. Pneumonia involving Aspergillus and Rhizopus spp. after a near-drowning incident with subsequent Nocardiacyriacigeorgici and N. farcinicacoinfection as a late complication. Eur J Clin Microbiol Infect Dis. 2005;24:61–4.CrossRefPubMedGoogle Scholar
- 3.Sarrami AH, Setareh M, Izadinejad M, Afshar-Moghaddam N, Baradaran-Mahdavi MM, Meidani M. Fatal disseminated mucormycosis in an immunocompotent patient: a case report and literature review. Int J Prev Med. 2013;4:1468–71.PubMedPubMedCentralGoogle Scholar
- 4.Kauffman CA, Malani AN. Zygomycosis: an emerging fungal infection with new options for management. Curr Infect Dis Rep. 2007;9:435–40.CrossRefPubMedGoogle Scholar
- 5.Spellberg B, Edwards J Jr, Ibrahim A. Novel perspectives on mucormycosis: pathophysiology, presentation, and management. Clin Microbiol Rev. 2005;18:556–69.CrossRefPubMedPubMedCentralGoogle Scholar
- 6.Chinn RY, Diamond RD. Generation of chemotactic factors by Rhizopus oryzae in the presence and absence of serum: relationship to hyphal damage mediated by human neutrophils and effects of hyperglycemia and ketoacidosis. Infect Immun. 1982;38:1123–9.PubMedPubMedCentralGoogle Scholar
- 7.Serio B, Rosamilio R, Giudice V, et al. Successful management of pulmonary mucormycosis with liposomal amphotericin B and surgery treatment: a case report. Infez Med. 2012;20:43–7.PubMedGoogle Scholar
- 8.Cornely OA, Arikan-Akdagli S, Dannaoui E, et al. ESCMID and ECMM joint clinical guidelines for the diagnosis and management of mucormycosis 2013. Clin Microbiol Infect. 2014;20:5–26.CrossRefPubMedGoogle Scholar
- 9.Almyroudis NG, Sutton DA, Fothergill AW, Rinaldi MG, Kusne S. In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents. Antimicrob Agent Chemother. 2007;51:2587–90.CrossRefGoogle Scholar
- 10.Vidovic A, Arsic-Arsenijevic V, Tomin D, et al. Proven invasive pulmonary mucormycosis successfully treated with amphotericin B and surgery in patient with acute myeloblastic leukemia: a case report. J Med Case Rep. 2013;7:263.CrossRefPubMedPubMedCentralGoogle Scholar
Copyright information
© Springer-Verlag Berlin Heidelberg 2015