Obesity not associated with severity among hospitalized adults with seasonal influenza virus infection
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We examined seasonal influenza severity [artificial ventilation, intensive care unit (ICU) admission, and radiographic-confirmed pneumonia] by weight category among adults hospitalized with laboratory-confirmed influenza. Using multivariate logistic regression models, we found no association between obesity or severe obesity and artificial ventilation or ICU admission; however, overweight and obese patients had decreased risk of pneumonia. Underweight was associated with pneumonia (adjusted odds ratio 1.31; 95 % confidence interval 1.04, 1.64).
KeywordsInfluenza Severe influenza Influenza hospitalizations Obesity BMI Body mass index
Kyle Openo MPH, and Monica M. Farley MD at the Georgia Emerging Infections Program; Joelle Nadle, MPH and Mirasol Apostol, MPH at the California Emerging Infections Program; Deborah Aragon, FluSurv-NET Coordinator at the Colorado Department of Public Health and Environment; Juliana Darrow, Veronica Fialkowski, Katelyn Hall, and Maryam Nuriyeva, Medical Record Abstractors, at the University of Colorado; Kimberly Yousey-Hindes, MPH, CPH at the Connecticut Emerging Infections Program; Maya Monroe, MPH at the Maryland Department of Health and Mental Hygiene; Matthew Laidler, MA, MPH, at the Oregon Public Health Division; Diane Brady, Consultant Public Health Nurse, Jessica Signore, Disease Intervention Specialist, and Daniela Quilliam, Chief of Acute Infectious Diseases; Karen Leib and Katie Dyer at the Vanderbilt University School of Medicine, Nashville, TN; Kathy Angeles, Lisa Butler, Sarah Khanlian, and Robert Mansmann, Surveillance Officers at the New Mexico Emerging Infections Program; Craig Morin at the Minnesota Department of Health The Influenza Hospitalization Surveillance Network (FluSurv-NET) is a collaboration of state health departments, academic institutions and local partners, and is funded by the Centers for Disease Control and Prevention (CDC). This publication was supported in part by Cooperative Agreement number CDC-RFA-CK12-1202 and 5U38HM000414 from CDC. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Centers for Disease Control and Prevention, US Department of Health and Human Services.
Conflict of interest
No potential conflict of interest.