Infection

, Volume 41, Issue 1, pp 199–202

Could anti-HCV treatment prevent recurrence of hepatocellular carcinoma in HIV-infected patients? Two case reports

  • G. Cenderello
  • E. Pontali
  • G. Cassola
  • A. Torresin
Brief Report

Abstract

Highly active antiretroviral therapy (HAART) has proven long-term efficacy in human immunodeficiency virus (HIV) infection. Combination therapy with pegylated interferon and ribavirin has become the standard of care in patients with both hepatitis C virus (HCV) chronic hepatitis and HIV/HCV co-infection. Data on the safety and efficacy of combination therapy in chronic hepatitis C patients with hepatocellular carcinoma (HCC) is scarce and even more so in HIV/HCV co-infected subjects. We report the successful administration of both HAART and anti-HCV therapies in two HIV/HCV co-infected patients after HCC eradication. These encouraging results might argue for the feasibility of an aggressive approach in the management of co-infected patients with HCC.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • G. Cenderello
    • 1
  • E. Pontali
    • 1
  • G. Cassola
    • 1
  • A. Torresin
    • 1
  1. 1.Department of Infectious DiseasesEO Ospedali GallieraGenoaItaly

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