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Infection

, Volume 36, Issue 2, pp 135–139 | Cite as

Seroepidemiology of Hepatitis B in Greek Children 6 Years After the Implementation of Universal Vaccination

  • V. Papaevangelou
  • C. Hadjichristodoulou
  • D. C. Cassimos
  • K. Pantelaki
  • A. Tzivaras
  • A. Hatzimichael
  • M. Theodoridou
Clinical and Epidemiological Study

Abstract

The seroepidemiology of hepatitis B in children living in Greece 6 years post-implementation of universal infant immunization (1998) was studied. We collected 90–100 sera/year of age, stratified by geographic region. The prevalence of HbsAg(+) was 0.6% (95% CI 0.3–1.3) whereas 4.5% (95% CI 3.4–5.9%) of children over 12 months of age had evidence of past HBV infection. A significant decline in the prevalence of past infection between children born before and after 1998 (5.5% vs 2.9%; RR = 1.9, 95% CI 1.03–3.5) was noted. Conversely, the prevalence of past HBV infection did not change significantly among immigrant children. Reinforcement of early vaccination of immigrant population is necessary.

Keywords

Immigrant Child Universal Vaccination Greek Child Universal Massive Vaccination Universal Infant Immunization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Urban & Vogel München 2008

Authors and Affiliations

  • V. Papaevangelou
    • 1
  • C. Hadjichristodoulou
    • 2
  • D. C. Cassimos
    • 3
  • K. Pantelaki
    • 4
  • A. Tzivaras
    • 4
  • A. Hatzimichael
    • 3
  • M. Theodoridou
    • 5
  1. 1.2nd Dept. of PediatricsUniversity of Athens, “A. Kyriakou” Children's HospitalGoudi, AthensGreece
  2. 2.Dept. of Hygiene and EpidemiologyFaculty of Medicine, University of ThessalyLarissaGreece
  3. 3.Dept. of PediatricsUniversity of ThraceAlexandroupoliGreece
  4. 4.Blood Bank Laboratory“A. Sofia” Children's HospitalGoudi, AthensGreece
  5. 5.First Dept. of PediatricsUniversity of Athens, “A. Sofia” Children's HospitalGoudi, AthensGreece

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