, 35:352 | Cite as

Serum Procalcitonin for Discrimination of Blood Contamination from Bloodstream Infection due to Coagulase-Negative Staphylococci

  • P. Schuetz
  • B. Mueller
  • A. TrampuzEmail author
Brief Report


The diagnostic value of serum procalcitonin (PCT) to distinguish blood contamination from bloodstream infection (BSI) due to coagulase-negative staphylococci was evaluated. Patients with BSI had higher PCT concentration than those with blood contamination at day –1, day 0 and day +1 with regard to blood culture collection (p < 0.05), whereas serum C-reactive protein values were significantly higher only on day +1. At a cutoff of 0.1 ng/dl, PCT had a sensitivity of 86% and 100%, and a specificity of 60% and 80% for the diagnosis of BSI on day –1 and 0, respectively. In addition to clinical and microbiological parameters, PCT may help discriminating blood contamination from BSI due coagulase-negative staphylococci.


Blood Culture Bloodstream Infection Procalcitonin Positive Blood Culture White Blood Count 
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Copyright information

© Urban & Vogel München 2007

Authors and Affiliations

  1. 1.Dept. of Internal MedicineUniversity Hospital BaselBaselSwitzerland
  2. 2.Dept. of Infectious Diseases and Hospital EpidemiologyUniversity Hospital BaselBaselSwitzerland

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