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Infection

, 35:352 | Cite as

Serum Procalcitonin for Discrimination of Blood Contamination from Bloodstream Infection due to Coagulase-Negative Staphylococci

  • P. Schuetz
  • B. Mueller
  • A. TrampuzEmail author
Brief Report

Abstract

The diagnostic value of serum procalcitonin (PCT) to distinguish blood contamination from bloodstream infection (BSI) due to coagulase-negative staphylococci was evaluated. Patients with BSI had higher PCT concentration than those with blood contamination at day –1, day 0 and day +1 with regard to blood culture collection (p < 0.05), whereas serum C-reactive protein values were significantly higher only on day +1. At a cutoff of 0.1 ng/dl, PCT had a sensitivity of 86% and 100%, and a specificity of 60% and 80% for the diagnosis of BSI on day –1 and 0, respectively. In addition to clinical and microbiological parameters, PCT may help discriminating blood contamination from BSI due coagulase-negative staphylococci.

Keywords

Blood Culture Bloodstream Infection Procalcitonin Positive Blood Culture White Blood Count 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Urban & Vogel München 2007

Authors and Affiliations

  1. 1.Dept. of Internal MedicineUniversity Hospital BaselBaselSwitzerland
  2. 2.Dept. of Infectious Diseases and Hospital EpidemiologyUniversity Hospital BaselBaselSwitzerland

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