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Infection

, Volume 35, Issue 4, pp 282–286 | Cite as

Reduced TH-1 Cytokine Release in an Adult Patient with Chronic Relapsing Mycobacterium malmoense Infection

  • U. Sahrbacher
  • L. Naumann
  • U. Reischl
  • J. Schölmerich
  • T. Glück
Case Report

Abstract

An unusual course of infection with Mycobacterium malmoense is described in a patient receiving chronic but mild immunosuppressive therapy for rheumatoid arthritis. Symptoms mimicking Crohn’s disease deteriorated under intensified immunosuppression and surgery. Judging from the patient’s course under treatment specific for M. malmoense, the gastrointestinal symptoms were rather manifestations of a chronic relapsing mycobacterial infection. Detailed immunological investigation of the patient revealed a severely impaired TH-1 cytokine response as the immunological background for this uncommon course.

Keywords

Peripheral Blood Mononuclear Cell Mycobacterium Rifabutin Mycobacterial Infection Sputum Smear 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Urban & Vogel München 2007

Authors and Affiliations

  • U. Sahrbacher
    • 2
  • L. Naumann
    • 3
  • U. Reischl
    • 3
  • J. Schölmerich
    • 2
  • T. Glück
    • 1
    • 2
  1. 1.Dept. of Internal MedicineKreisklinik TrostbergTrostbergGermany
  2. 2.Dept. of Internal Medicine IUniversity Medical Center, University of RegensburgRegensburgGermany
  3. 3.Institute of Medical Microbiology and HygieneUniversity of RegensburgRegensburgGermany

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